September 2024 – Page 99

Making a Splash in Germany, NEOMOR Shines at the IAA TRANSPORTATION 2024

On September 17th 2024, at the IAA TRANSPORTATION 2024 in Hannover, Germany, all eyes in the last-mile delivery market were on NEOMOR (Booth F29, Hall 14), more specifically, NEOMOR D01.

The brand presented to the European market its new generation of logistics vehicles – NEOMOR D01 Micro Cargo and Micro Truck, which has got the EU L7e type approval.

With its agility, reliability, economic advantages, and outstanding design, this electric logistics vehicle has significantly improved the efficiency and working environment of last-mile delivery, bringing revolutionary changes to the field. Since its launch, the model has been applied to than 40 scenarios including mobile vending, municipal services, and cold-chain delivery.

For the European market, NEOMOR D01 fits smoothly in narrow streets and historic town centers, and adapts perfectly to the needs of local logistics company, car-rental company with its long battery life, low energy consumption and excellent design.

Participating in the IAA TRANSPORTATION is a continuation of the achievements made in the European market and an important milestone in NEOMOR’s global expansion strategy. Europe is not only a springboard for the brand’s global market layout but also a touchstone for testing product quality and market competitiveness. Looking ahead, NEOMOR will continue to adhere to the “user-centered” philosophy, continuously innovate and improve its product lines, enhance service quality, and strive to become a leading enterprise in the global new energy logistics vehicle field.

Media Contact
Company Name: DERRY New Energy Automobile Co., Ltd.
Contact Person: Renhong Fang(Andy)
Email: Send Email
Phone: +86 186 7189 7590
City: Shanghai
Country: China
Website: www.neomor-ev.com

From Mooncakes to Jewelry to Celebrity Endorsements: This Chinese Game is Making Waves

September 17th marks the Mid-Autumn Festival in China, where people traditionally indulge in mooncakes. This year, a particular mooncake from China has gained widespread popularity. Suzhou’s provincial-level intangible cultural heritage project, the protective unit of Suzhou-style mooncake making techniques, Daoxiangcun, collaborated with the popular game “Black Myth: Wukong” to launch a “Qi Tian Lan Yue” mooncake gift box priced at 99 RMB. Upon its release, it became an instant hit, with buyers exclaiming, “How can one bring themselves to eat this?”

“Black Myth: Wukong” has also been making waves in the cross-border e-commerce sector recently. Shortly after its release, TikTok influencer @barbiegoodies.us swiftly created short videos incorporating the game’s storyline to promote a set of four jewelry memorabilia. Renowned Chinese jewelry brands like Lao Fengxiang and Qupite have also embedded “Black Myth: Wukong” elements into their jewelry designs. Chow Tai Fook’s earlier release of a 1.8 million RMB solid gold Monkey King’s staff has also unexpectedly gained traction due to the recent popularity of “Black Myth: Wukong,” frequently trending on social media. Currently, this auspicious gold staff, weighing 7,616.06 grams with 1,755 grams of gold and measuring 2016.28 millimeters in length, is being exhibited at Xi’an SEG International Shopping Mall.

Apart from its success in merchandise sales, “Black Myth: Wukong” has also garnered celebrity endorsements. Elon Musk, the world’s richest man and tech giant, shared a photo of himself with an AI-generated image of “Black Myth: Wukong” on his social media platform X, commenting, “An impressive AAA game from China! Seems oddly familiar.” This post garnered over 62 million views, sparking various interpretations and a wave of shares on social media. What magic does this game possess? What does its popularity signify?

The explosive popularity of “Black Myth: Wukong” highlights a significant improvement in China’s game industrialization level. Drawing inspiration from one of China’s Four Great Classical Novels, “Journey to the West,” “Black Myth: Wukong” quickly topped the sales charts on platforms like Steam and WeGame since its official release on August 20th, selling over 4.5 million copies on its first day and remaining at the top of Steam’s global charts for five consecutive weeks. According to VG Insights, as of September 12th, the game had sold over 18.9 million copies globally within just two weeks, generating over $905 million in revenue, equivalent to over 6.4 billion RMB. With its stunning graphics, intricate gameplay design, and robust cultural tourism integrations, this game has sparked a wave of Chinese fantasy gaming among global players, showcasing Chinese mythology, traditions, culture, and real-life locations to the world.

“Black Myth: Wukong” enhances the global appeal of Chinese culture. In recent years, China has produced a series of well-crafted cultural products such as “The Wandering Earth,” “Three Thousand Miles of Chang’an,” and “My Altay,” marking significant improvements in the quality of Chinese cultural products. As globalization accelerates and technological advancements continue, cross-regional cultural exchanges have become increasingly frequent. Games, as globally influential cultural and creative products, play a crucial role in bridging different cultures and have become an important means for countries to showcase their cultural soft power.

“Black Myth: Wukong,” with its inherent strong Chinese cultural symbols, owes its success not only to its exceptional gameplay quality but also to its unique cultural charm and global perspective. Its meteoric rise not only fills the gap in China’s AAA game industry but also signifies a breakthrough for Chinese cultural products, marking their advancement towards premiumization and internationalization.

Media Contact
Company Name: Suzhou Xinhuaxing Information Technology Co., Ltd.
Contact Person: Wang He
Email: Send Email
City: SuZhou
Country: China
Website: www.xing-group.cn

Why Good Publicity Is Critical to a Brand’s Success According to 9-Figure Media

Public relations, also known as PR, simply means how businesses and brands pass positive information themselves to the public. Businesses use PR to influence the perception of people. And although PR can reach more people, it is often overlooked by the media.

Even still, some businesses have not realized how good publicity is critical to their brand. Read on to find out 5 reasons why good publicity is critical to your brand, according to 9-Figure Media. This is especially important if you’re a startup brand looking for the best PR agencies for startups to push your brand to the next level.

1. Builds Trust

One major thing most businesses struggle with is building trust and credibility with their customers. Companies that write about their business operations are seen as blowing their own horns.

Trust has its advantages, and PR is a medium for these businesses to earn it. PR gives honest opinions and reviews of your company, by their parties. This is why PR is powerufl tool for companies looking to grow, hence a startup PR company can change your startup business beyond your wildest imagination.

2. Lead Generation

PR is a great way for businesses to generate quality leads. It is both a short-term and long-term lead generation tool proven effective when used over time. Smart business owners deploy PR to gain both credibility and bring in quality leads for their businesses.

Crafting compelling messages works in synergy with already boosted credibility to bring in new customers and maintain loyal ones.

3. PR sets your business aside as an industry leader

Apart from helping businesses generate quality leads, PR also sets a business as an industry expert and leader. It also positively separates you from your competitors. PR also helps business owners show consumers their experience, and skills.

PR is an opportunity for a business owner to tell prospective clients how their business offers value. It also serves as a platform, giving detailed reasons why you should be trusted and why your business idea should be brought against your competitors.

4. Greater Reach

A well-crafted PR campaign can reach your target audience and might even be read internationally. With the popularity of the internet, and social media, PR helps businesses grow and build their brand.

Smart business owners like you should leverage on the use of PR to reach a greater number of your audience. The mind-blowing effect a good PR campaign gets is worth the investment. That’s a very important point in choosing startup PR agency like 9FigureMedia for your business.

5. Helps with SEO

Great PR helps with SEO ranking of your website. It is interesting to know that 75% of people never scroll past the first page when they type in a query in the search engine. And since SEO is now a fancy word, businesses topple one another in a bid to rank higher in the first page of a search engine.

This is where good PR comes in. By telling your target audience how great your business idea is, and why they should trust you, your website gets the sought-after position of being in the first upper page of search engines.

9 Figure Media uses the right PR approach to help businesses reach their goals. Businesses benefit from their massive news distribution networks, including trustworthy ones to boost their brand awareness.

To position your business as credible, their team creates articles to promote a positive image of your brand. All these help increase sales for your business in the long run.

Media Contact
Company Name: 9-Figure Media Public Relations
Contact Person: Chris James
Email: Send Email
Phone: 9493426155
Address:1986 South Coast Highway
City: Laguna beach
State: CA
Country: United States
Website: https://9figuremedia.com

MythicVoice LLC Launches Premium Wedding Photography Services, Capturing Authentic Moments in Atlanta, Georgia

Capturing timeless moments with a touch of artistry, MythicVoice LLC brings your story to life through the lens, one perfect shot at a time

Offering wedding photography in Atlanta, MythicVoice LLC stands out among photographers in Atlanta, GA, for capturing unique love stories and elopements

MythicVoice LLC announces its premium wedding photography services, offering unparalleled expertise and creativity for couples seeking to capture their special day. Founded by Omotola Ajibade, a professional photographer in Atlanta, GA, MythicVoice LLC combines storytelling with photography to curate unforgettable images that reflect the essence of every moment.

Image by MythicVoice LLC

“MythicVoice LLC was built on the belief that the best stories are forged in connections between people, places, and experiences,” says Omotola Ajibade, Founder of MythicVoice LLC. “Our goal is to create images that are not just beautiful, but also meaningful and true to each couple’s unique journey.”

Image by MythicVoice LLC

As one of the best Atlanta photographers, MythicVoice LLC offers a seamless 4-step process designed to ensure an exceptional experience from start to finish. This includes an in-depth consultation to understand the couple’s vision, capturing the big day with authenticity and creativity, a personalized viewing session, and finally, delivering high-quality, hand-inspected prints and albums.

Image by MythicVoice LLC

Specializing in wedding photography in Atlanta, the company is also known for documenting intimate Atlanta elopements, bringing a blend of artistry and emotion to every shot. Omotola Ajibade’s unique approach and dedication to capturing the true essence of each moment distinguish MythicVoice LLC among wedding photographers in Atlanta, GA.

Image by MythicVoice LLC

MythicVoice LLC offers a range of high-quality products to preserve and showcase cherished memories, including:

Heirloom Albums: Crafted with various cover materials, these albums offer a timeless way for generations to enjoy images.
Canvas and Metal Prints: Luxurious and contemporary prints ready to hang, adding a touch of elegance to any space.
Folio Boxes: Hand-crafted boxes holding up to 20 board-mounted or matted prints, offering a versatile yet affordable display.
Framed Wall Art: Timeless fine art prints ready to decorate homes, serving as daily reminders of perfect moments.

MythicVoice LLC, founded by Omotola Ajibade, a professional photographer in Atlanta, GA, specializes in capturing life’s most meaningful stories through a lens. Renowned among photographers in Atlanta, Georgia, the company offers a range of photography services including weddings, elopements, and portrait sessions. With a commitment to providing a personalized and exceptional experience, MythicVoice LLC ensures that every story is beautifully told through images.

For more information about MythicVoice LLC’s wedding photography services or to schedule a consultation, visit https://www.mythicvoice.com/.

Media Contact
Company Name: MythicVoice LLC
Contact Person: Omotola K Ajibade
Email: Send Email
Phone: 404-507-2987
City: Atlanta
State: Georgia
Country: United States
Website: https://www.mythicvoice.com/

Cash Offer Man Expands Into All Missouri Markets Enabling Homeowners To Sell Their Homes Fast and Efficiently

Cash Offer Man announces an expansion into all Missouri markets. Cash Offer Man has provided access to quick and easy home sales throughout neighboring markets and due to customer demand expanded quickly into all major markets in the region. Furthermore, Cash Offer Man has introduced a helpful service that allows homeowners to sell their properties for cash before relocating. Homeowners in the area who want cash for their home can receive a free offer.

Missouri – Cash Offer Man, headed by Aaron Eller, buys houses in all Missouri counties. The company that buys houses gives cash for properties anywhere in Missouri and are committed real estate investors in the region. Cash Offer Man guiding principles is to stay small and lightweight to afford giving the homeowner the highest possible cash offer for their house. Therefore, the company does everything from acquiring properties, overseeing renovations, and marketing. They keep their margins modest and work with local Missouri contractors to keep repair costs low. Cash Offer Man also enjoys assisting homeowners in escaping less-than-ideal situations and undertaking renovation projects of any size.

Instead of paying a commission and waiting months to sell a home, Cash Offer Man makes it fast and easy by making repairs, cleaning, and buying in cash so there’s no financing. You don’t have to deal with locating a real estate agent, or dealing with open houses and showings. They take up the home seller’s position and, in so doing, make life easy for them. Cash Offer Man buys houses in any condition for cash in Missouri, which means that sellers can earn cash for their house while saving tens of thousands of dollars and a significant amount of time.

Since 2023, Cash Offer Man has been making cash offers to homeowners who want to sell a house, townhome, condo, or apartment that they no longer want. Sellers will receive cash for their homes regardless of their situation from having trouble paying their mortgage, trying to prevent foreclosure, or needing some extra income, to any other reason, such as not wanting to deal with realtors. Cash Offer Man takes pride in providing property owners in Missouri and the surrounding areas with direct selling benefits. The home buyers at Cash Offer Man are people-oriented, and they take satisfaction in listening to the sellers’ inquiries while properly explaining the home sale process to them.

Property owners in and around Missouri and surrounding areas can rest easy knowing that they will have access to a faster home sale process, one that can be completed in 7 days or on the seller’s timeline. They will also be saving money on commissions, agent fees, closing costs, and more with the help of Cash Offer Man.

To learn more about Cash Offer Man, Contact them via phone at (314) 912-4939. For more information, visit their website.

Media Contact
Company Name: Cash Offer Man
Contact Person: Aaron Eller
Email: Send Email
Phone: (314) 912-4939
Address:4620 S St Peters Pkwy
City: Saint Charles
State: Missouri 63304
Country: United States
Website: www.cashofferman.com/

Kavy’s Customs Brings Professional, Creative Apparel Solutions to Businesses and People in California

A woman-owned business, founded by Kavy Pounds, creates unique, high-quality custom embroidery and t-shirt printing for businesses and events.

Kavy’s Customs, a woman-owned custom apparel company, is making waves in the industry with its focus on creativity, quality, and accessibility. Launched by Kavy Pounds at just 16 years old, the business now thrives two years later, serving clients such as Green Dot Public Schools by providing custom uniforms and apparel for staff and security. As the company continues to grow, Kavy’s goal is to expand and establish multiple storefronts within five years.

Specializing in custom embroidery and direct-to-film (DTF) printing, Kavy’s Customs offers personalized apparel with no minimum order quantities. Whether for business branding, events, or casual wear, the company prides itself on delivering high-quality products that help businesses and individuals stand out. Its range of services includes custom t-shirt printing, embroidery, and work uniforms, featuring top brands like Nike, OGIO, Sport-Tek, and Carhartt.

What sets Kavy’s Customs apart is its commitment to supporting other women-owned businesses. By offering personalized service and no hidden costs, Kavy’s Customs provides an inclusive and accessible way for businesses to create branded apparel without the hassle of complex pricing or order minimums.

“We aim to bring logos and designs to life with our custom apparel solutions,” says Kavy Pounds, founder and owner. “Whether it’s for corporate events, team uniforms, or special celebrations, we strive to provide the best quality and creative solutions to meet every need.”

Kavy’s Customs ensures that every client receives expert assistance throughout the process, from selecting the right item to finalizing designs. Built on creativity and originality, the team is dedicated to transforming logos and designs into wearable art, allowing businesses and individuals to express their unique identities. The company brings each design to life with meticulous attention to detail, ensuring that every order captures the client’s vision may the order be for corporate apparel, casual wear, or special events.

Kavy’s Customs offers a seamless process for custom orders: clients select their item, upload a logo or design, and approve the final product before it goes into production. With no minimum order quantities, Kavy’s Customs makes it easy for businesses of all sizes to access custom apparel. Pricing is inclusive of free design review and shipping on orders over $75, with bulk discounts available.

As Kavy looks to the future, her goal is to expand Kavy’s Customs with multiple storefronts within the next five years. By focusing on quality, innovation, and customer satisfaction, she continues to carve out a space for her brand in the competitive custom apparel industry.

For more information on Kavy’s Customs and their services, visit kavyscustoms.com.

About Kavys Customs

Kavy’s Customs is a woman-owned custom apparel business specializing in personalized embroidery and Direct-to-Film (DTF) printing. Based in Temecula, California, the company offers high-quality, premium branded apparel with no minimum order requirements, serving businesses and individuals seeking creative, custom designs.

Media Contact
Company Name: Kavys Customs
Contact Person: Kavy Pounds
Email: Send Email
Phone: 951-805-1650
Country: United States
Website: https://kavyscustoms.com/

Bella Reina Spa Introduces Oncology Facials with Innovative Skin Diva Labs Products

Delray Beach, FL – September 19, 2024 – Bella Reina Spa, a leading wellness destination in Delray Beach, FL., is proud to announce the launch of its specialized Oncology Facial treatments. This new service is designed to address cancer patients’ and survivors’ unique skincare needs, offering a safe and nurturing experience during a challenging time.

Bella Reina Spa

The Oncology Facial at Bella Reina Spa utilizes the pioneered vegan skincare line Skin Diva Labs, specifically formulated to be safe for cancer or recovery patients. This non-toxic, fragrance-free product range is power-packed with gentle yet effective ingredients that cater to sensitive skin.

The commitment to Oncology facials and skincare began when some of the Bella Reina clients had cancer. Their regular treatments and facials were too much for their skin. This started a quest to develop skincare that was so amazing; it powerfully changed the skin, yet it was so gentle there were no reactions, only soft, glowing, and gorgeous skin.

“We understand the devastating toll cancer treatments can take on a person’s skin and overall well-being,” says Nancy Reagan, owner of Bella Reina Spa. “Our Oncology Facials are more than just a skincare treatment – they’re a lifeline for those seeking comfort and glowing skin during their cancer journey.”

The Oncology Facial treatment at Bella Reina Spa includes carefully curated steps, including gentle cleansing, fruit enzymes, and a velvety blue mask, all powered by emulsifier-free products. Of course, relaxation and stress techniques are key to this treatment, with light touch-point massages throughout the facial.

Bella Reina Spa’s oncology aestheticians are specially trained to work with cancer patients and survivors, ensuring a safe and beneficial experience. All cancer patients currently undergoing chemotherapy or radiation are required to consult their oncologist and receive written approval prior to treatment.

For more information about Oncology Facials at Bella Reina Spa or to schedule an appointment, please visit https://bellareinaspa.com/oncology-facials-treatments-and-oncology-skincare/ or call (561) 404-7670.

About Bella Reina Spa:

Bella Reina Spa is a premier wellness facial spa in Delray Beach, FL, offering a range of facials, medical facials, and skincare treatments. Focusing on holistic well-being and innovative skincare solutions, Bella Reina Spa’s mission is to keep you going and going, no matter your age.

About Skin Diva Labs

Skin Diva Labs isn’t just another skincare brand—it’s a revolution in ethical beauty. Born from a fierce dedication to clean, cruelty-free practices, Skin Diva Labs dares to blend revolutionary luxury with sustainability. Every product is a bold statement, meticulously crafted from the finest plant-based ingredients to deliver powerful results without compromise. This is skincare reimagined, where the harmony of science and nature meets a radical respect for the planet. Welcome to the future of beauty, where every choice stands for care, compassion, and conscious living.

Media Contact:

Nancy Reagan

Owner, Bella Reina Spa

Phone: (561) 404-7670

Email: info@bellareinaspa.com

Media Contact
Company Name: Bella Reina Spa
Contact Person: Nancy Reagan
Email: Send Email
Phone: (561) 404-7670
Country: United States
Website: https://bellareinaspa.com/

Peace projects in 170 countries: HWPL celebrates decade of global commitment to peace

HWPL stated that the purpose of the anniversary is to review achievements since 2014 and discuss future plans. Through 10 years of international cooperation for peace, HWPL has 500,000 members in 170 countries and is carrying out peace projects.

Sydney, Australia – From September 18, 2024, the 10th Anniversary of the HWPL World Peace Summit is being celebrated in South Korea and various locations worldwide reaching 122 countries.

Under the theme ‘Creating World Peace Community through Regional Collaboration’, this event commemorates global leaders’ and citizens’ commitment to peace that lasted for a decade, with an eye towards future strategies to promote global harmony.

HWPL stated that the purpose of the anniversary is to review achievements since 2014 and discuss future plans.

Various sessions are being held in each country at different levels to gather regional talents and establish networks essential for tailored peace strategies, strengthening regional networks to tackle local peace threats, and harnessing collective capacities.

Headquartered in Seoul, South Korea, Heavenly Culture, World Peace, Restoration of Light (HWPL) is an international NGO affiliated with UN ECOSOC.

Through 10 years of international cooperation for peace, HWPL has 500,000 members in 170 countries and is carrying out peace projects through MOAs or MOUs with 1,014 organizations in 105 countries.

Chairman Lee Man-hee of HWPL pointed out that the division of religion caused tremendous loss of life, emphasizing that religions must take the lead in dialogue and understanding.

“We must work together to create a world of peace and leave it as a legacy for future generations. This is to fulfill our mission as a light that brings life to the global village. Only through love and peace can the world become one,” he said.

In line with the event keyword of regional cooperation, HWPL formed a partnership with the intergovernmental organization Group of 7+ (G7+) and a high-level political forum organization, The Latin American Parliament (Parlatino), to develop peace initiatives.

The G7+ was established to unite conflict-affected countries with a vision of peace, stability, and development, with 20 member states, and PALATINO was founded to promote development and integration within a framework of full democracy, having 23 member states.

A peace project in Timor-Leste presented by the Minister of Higher Education, Science and Culture, Dr. Jose Honorio da Costa Pereira Jeronimo.

He explained that the Ministry and eight higher education institutions partnered with HWPL to introduce peace education in the country.

“I believe that peace education will play a crucial role, not just as a simple subject, but in helping students grow into future global citizens and in laying the foundation for peace and stability across society,” he said.

H.E. Prof, Dr. Emil Constantinescu, the 3rd President of Romania and President of Institute for Advanced Studies in Levant Culture and Civilization reminded participants of the 2014 HWPL summit that advocated international cooperation for peace building.

“An incredible and impressive image proves that the faith in global peace is very much more than a mere initiative. It was then that I first truly felt that we are all one and be irrespective of our perceived differences. We are all united in one breath in the service of the greater calling of global peace.”

This peace summit engages social representatives in peace projects in different countries.

In South Korea, the ‘Together: Connecting Korea’ officially launched a national campaign for social harmony.

Aligning with 230 civil society organizations, this campaign connects generations and diverse cultures and carries out various environmental protection activities.

Media Contact
Company Name: HWPL NSW
Contact Person: Tracy
Email: Send Email
Phone: +61403178414
City: Sydney
State: NSW 2000
Country: Australia
Website: https://www.hwpl.kr/language/en/home-hwpl-_en/

Industry Update: 3 Exciting Precision Oncology Players to Watch Following Summit’s Meteoric Rise: Silexion, Nuvectis, Scorpian

Summit Therapeutics’ rise could signal emerging opportunities in precision oncology such Nuvectis Pharma (NASDAQ: NVCT), Silexion (NASDAQ:SLXN), and Scorpion leading the charge.

Summit Therapeutics (NASDAQ: SMMT) recently captured headlines with the release of its Phase 3 data for ivonescimab, a targeted NSCLC therapy that has generated substantial buzz. The results from its trial conducted in China showed a dramatic 49% reduction in the risk of disease progression or death compared to Merck’s Keytruda, signaling a potentially disruptive force in NSCLC treatment. However, the news wasn’t without its concerns—since the trial data originates from China, there are questions about its applicability to broader, global populations. As noted by BMO Capital Markets’ Evan Seigerman: “Results may or may not be generalizable beyond the China-focused patient population initially assessed.” Despite this, Summit’s valuation has risen by over 100%, now approximating $19 billion. With such a high valuation, the company could see limited room for further significant gains, leading many in the industry to explore other emerging opportunities in precision oncology.

Alongside Summit, there are quite a few other players in the field. Some if these companies have even already shown promising initial results and could see similar success in the future if they were to report positive results. These emerging players are worth watching for those interested in following precision oncology drug candidates and pipelines. Among them are precision oncology innovators such as Silexion Therapeutics, Nuvectis Pharma, and Scorpion Therapeutics, which we discuss below.

Silexion Therapeutics: Disrupting the KRAS-Driven Cancer Space

Silexion Therapeutics (NASDAQ: SLXN) is another under-the-radar player in the precision oncology space, with a focus on KRAS-driven cancers—a notoriously difficult target in oncology. While current small-molecule KRAS inhibitors are making progress, they are often limited to specific mutations, such as KRAS G12C, which accounts for a small percentage of cancers. Silexion’s RNA interference (RNAi) approach offers a broader solution, targeting a wider spectrum of KRAS mutations, particularly in pancreatic cancer, one of the deadliest and most treatment-resistant cancers.

At the heart of Silexion’s approach is its LODER™ platform, which delivers siRNA directly to the tumor site, silencing KRAS mutations at the genetic level. This localized delivery not only increases efficacy by concentrating the treatment in the tumor, but it also reduces systemic side effects. Silexion’s next-generation candidate, SIL-204, is an optimized siRNA formulation designed to target pan-KRAS G12x mutations, positioning it to treat a broader range of KRAS-driven cancers beyond pancreatic cancer, such as lung and colorectal cancers.

In Phase 2 trials for locally advanced pancreatic cancer, Silexion’s LODER™ platform showed a 9.3-month improvement in overall survival when combined with standard chemotherapy. Additionally, the objective response rate (ORR) increased from 20% with chemotherapy alone to 55% with the combination, and in some cases, tumors that were initially non-resectable became operable after treatment with LODER™. These results are especially encouraging given the limited options available for pancreatic cancer patients. SIL-204, is expected to enter Phase 2/3 clinical trials in 2025-2026.

What makes Silexion particularly intriguing is its current market valuation. Valued at aproximatly just ~$9 million following its SPAC merger, the company’s valuation could be perceived as low when compared to some of its peers, especially given its innovative technology and promising clinical achievements. Some have wondered whether this low valuation has more to do with dynamics post-SPAC companies. If Silexion can report positive results in its later-stage trials, the company’s outlook could dramatically improve, reflecting the potential of its RNAi-based platform. Like NXP900, SIL-204 could potentially have vast applications across multiple KRAS-driven cancer types, making Silexion a company to watch closely as it advances through clinical development.

Nuvectis Pharma: Targeting NSCLC and Beyond by Inhibiting SRC/YES1 Kinases

Nuvectis Pharma (NASDAQ: NVCT) has been quietly making strides in the precision oncology sector, developing innovative therapies aimed at overcoming treatment resistance in hard-to-treat cancers. Its lead candidate, NXP900, targets NSCLC by inhibiting the SRC/YES1 kinases, which play critical roles in cancer cell survival and resistance to current therapies. This approach positions NXP900 as a potential game-changer in the treatment of NSCLC, particularly in patients who have developed resistance to EGFR and ALK inhibitors, such as AstraZeneca’s Tagrisso and Novartis’ Alecensa.

NXP900 is still in the early stages of clinical development, currently undergoing Phase 1 trials. However, preclinical studies have already shown that it has strong anti-tumor activity in resistant NSCLC models. Even more promising is its potential application beyond NSCLC. Like Summit’s ivonescimab, NXP900 focuses on resistance, but it also has broader applications due to its ability to target multiple cancer types driven by SRC/YES1 pathways. This versatility makes it a promising asset not just for NSCLC but also for other difficult-to-treat cancers like squamous cell carcinomas.

In addition to NXP900, Nuvectis is advancing NXP800, another precision oncology candidate that is further along in the clinical development process. NXP800 is currently in Phase 1b trials, targeting ARID1a-mutated cancers such as ovarian and endometrial cancers. The early clinical data for NXP800 is promising, showing positive responses in patients with platinum-resistant ovarian cancer. With two strong candidates in the pipeline, Nuvectis is positioning itself as a formidable player in the precision oncology landscape. As Summit’s ivonescimab continues to gain attention, Nuvectis’ earlier-stage NXP900, with its NSCLC focus and beyond, could see similar success in the future if clinical results continue to trend positively.

Scorpion Therapeutics: Pioneering Mutant-Selective Therapies

Scorpion Therapeutics is redefining the frontier of precision oncology with its focus on delivering highly selective small molecules targeting validated and previously undruggable cancer mutations. Its lead candidate, STX-478, is a mutant-selective, allosteric PI3Kα inhibitor currently in Phase 1/2 trials for advanced solid tumors. Early data presented at the ESMO Congress 2024 highlighted its potential, with STX-478 demonstrating a 23% overall response rate in breast cancer and a 21% response rate across all tumor types, positioning it as a potentially best-in-class PI3Kα inhibitor.

STX-478 is notable for its ability to spare wild-type PI3Kα activity in normal tissues, avoiding the toxicities seen with previous PI3Kα inhibitors, such as hyperglycemia and rash. Tumor reductions were seen in 72% of patients treated with STX-478 as a monotherapy, with circulating tumor DNA levels dropping in 86% of patients. This mutant-selective precision could help overcome the limitations of existing PI3Kα inhibitors, which have struggled with dose-limiting toxicities.

In July 2024, Scorpion raised $150 million in a Series C financing round, co-led by Frazier Life Sciences and Lightspeed Venture Partners. The additional funding will support the advancement of STX-478 and other pipeline assets, positioning Scorpion for further clinical success. Scorpion’s pipeline includes a broad range of wholly-owned compounds that target both validated and novel cancer targets, positioning the company for future expansion into larger patient populations. As STX-478 progresses through clinical development, Scorpion is poised to become a significant player in the precision oncology space, making it another company worth watching closely.

Optimistic Outlook for Precision Oncology

The precision oncology space is experiencing a golden era of innovation, with companies like Summit Therapeutics, Nuvectis Pharma, Silexion Therapeutics, and Scorpion Therapeutics leading the charge. As the focus shifts towards targeted therapies that address resistance mechanisms, the market is increasingly favoring companies with novel approaches and broad applications. Summit’s meteoric rise has shown that there is tremendous potential for companies that can demonstrate efficacy in overcoming cancer resistance. While Summit has already captured much of the current attention, companies like Nuvectis, Silexion, and Scorpion, with their earlier-stage pipelines, offer exciting opportunities for the industry to keep a close eye on.

As these companies continue to report clinical data and advance through trials, the potential for breakthroughs in treating some of the most difficult cancers grows stronger. With targeted therapies offering the possibility of overcoming resistance without the need for chemotherapy, the future of cancer treatment looks brighter than ever. For those in the oncology space, keeping a close eye on emerging players like Nuvectis, Silexion, and Scorpion could lead to transformative developments as the field of precision oncology continues to evolve.

This update may include speculative forward looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. the BioTech and Pharma industries are volatile and risky and readers are advised to seek out preffesional advice in the relevent feilds from licensed profesionals.

This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [https://justpaste.it/ch2qt/pdf]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest.

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Black in Marine Science announces new chief innovation officer Germain Bebe

Miami, FL – Sep 19, 2024 – Black in Marine Science (BIMS) is proud to announce the appointment of Germain Bebe as Chief Innovation Officer (CIO), in addition to his current role as Chief Operating Officer (COO). A dynamic leader with a decade of experience spanning the non-profit, climate-tech, and technology sectors, Bebe will spearhead BIMS’s initiatives to drive innovation, develop groundbreaking programs, and cultivate strategic partnerships.

“Germain’s passion for marine science, strategic vision, and leadership abilities, paired with his extensive experience in organizational growth and technological innovation, make him an exceptional fit for this role,” said Dr. Tiara Moore, Founder and CEO of BIMS. “We are confident that he will accelerate our mission to celebrate Black marine scientists, foster environmental awareness, and inspire future generations of scientific leaders.”

As CIO, Bebe will focus on identifying and developing new opportunities for BIMS to amplify its impact and reach. Leveraging his background in Generative AI and product commercialization, Germain will lead innovative AI solutions to address environmental justice and ocean conservation issues. Additionally, he will cultivate strategic partnerships with other organizations and institutions to further BIMS’ goals.

“I am deeply honored to be appointed as CIO of BIMS,” said Bebe. “I am eager to collaborate with our talented team to develop pioneering approaches that advance our mission. By combining technological innovation with social awareness and data democratization, we will create a more inclusive and equitable marine science field and inspire the next generation of leaders.”

Bebe’s dedication to using technology to combat climate change and advocate for ocean and environmental justice aligns seamlessly with BIMS’ core values. His leadership will be instrumental in shaping the future of the organization and driving its continued success.

About Black in Marine Science:

Black in Marine Science is a nonprofit organization dedicated to celebrating Black marine scientists, spreading environmental awareness, and inspiring the next generation of scientific leaders. BIMS provides a platform for Black marine scientists to share their work, connect with each other, and access resources and opportunities. BIMS also works to increase diversity and inclusion in the marine science field.

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Alexia McKay

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alexia.mckay@otterpr.com

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