Month: July 2024

“Leptomeningeal Metastases Pipeline”

(Las Vegas, Nevada, United States) As per DelveInsight’s assessment, globally, Leptomeningeal Metastases pipeline constitutes 5+ key companies continuously working towards developing 5+ Leptomeningeal Metastases treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

“Leptomeningeal Metastases Pipeline Insight, 2024″ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Leptomeningeal Metastases Market.

The Leptomeningeal Metastases Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

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Some of the key takeaways from the Leptomeningeal Metastases Pipeline Report:

• Leptomeningeal Metastases Companies across the globe are diligently working toward developing novel Leptomeningeal Metastases treatment therapies with a considerable amount of success over the years. 
• Leptomeningeal Metastases companies working in the treatment market are Plus Therapeutics, AstraZeneca, Angiochem, Y-mAbs Therapeutics, TYK Medicines, Inc, Seagen Inc., Pfizer, Genentech, Inc., Angiochem Inc, Daiichi Sankyo, Inc., and others, are developing therapies for the Leptomeningeal Metastases treatment 
• Emerging Leptomeningeal Metastases therapies such as Rhenium-186 NanoLiposome (186RNL), AZD1390, Paclitaxel trevatide (ANG1005), Omburtamab, and others are expected to have a significant impact on the Leptomeningeal Metastases market in the coming years.
• On January 2024, Plus Therapeutics announced results of a Multicenter Phase 1 Clinical Study to Determine the Maximum Tolerated Dose/Maximum Feasible Dose, Safety, & Efficacy of Single Dose Rhenium-186 NanoLiposome (186RNL) Administered via Intraventricular Catheter for Leptomeningeal Metastases.
• On April 2023, Angiochem announced results of a Randomized Open-Label, Multi-Center Pivotal Study of ANG1005 Compared with Physician’s Best Choice in HER2-Negative Breast Cancer Patients with Newly Diagnosed Leptomeningeal Carcinomatosis and Previously Treated Brain Metastases (ANGLeD).
• On March 2022, Kadmon Corporation announced results of A Phase 2, Multicenter Study of Tesevatinib in Subjects with Non-Small Cell Lung Cancer, EGFR Activating Mutation, Prior Treatment With a Tyrosine Kinase Inhibitor, and Brain Metastases or Leptomeningeal Metastases.

Leptomeningeal Metastases Overview

Leptomeningeal metastases (LM), also known as leptomeningeal carcinomatosis, is a severe and advanced complication of cancer where malignant cells spread to the leptomeninges, the two innermost layers of tissue covering the brain and spinal cord. This condition occurs in 5-8% of all cancer patients, with higher incidences in those with cancers of the breast, lung, and melanoma.

Leptomeningeal metastases occurs when cancer cells migrate through the bloodstream or directly invade the cerebrospinal fluid (CSF). These cells can then disseminate throughout the central nervous system (CNS), leading to widespread neurological symptoms. Common Leptomeningeal metastases symptoms include headache, nausea, vomiting, changes in mental status, cranial nerve deficits, back pain, and motor or sensory disturbances.

Diagnosis of Leptomeningeal metastases typically involves imaging studies like MRI, which can reveal abnormalities in the meninges, and lumbar puncture to analyze CSF for malignant cells or elevated protein levels

Treatment options for Leptomeningeal metastases are limited and primarily palliative, focusing on alleviating symptoms and improving quality of life. They include intrathecal chemotherapy (delivered directly into the CSF), systemic chemotherapy, radiation therapy, and corticosteroids to reduce inflammation and pressure. Despite treatment, the prognosis for Leptomeningeal metastases remains poor, with a median survival time of a few months. Early detection and intervention are crucial for managing symptoms and prolonging survival.

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Leptomeningeal Metastases Route of Administration

Leptomeningeal Metastases pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

Leptomeningeal Metastases Molecule Type

Leptomeningeal Metastases Products have been categorized under various Molecule types, such as

• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Leptomeningeal Metastases Pipeline Therapeutics Assessment

• Leptomeningeal Metastases Assessment by Product Type
• Leptomeningeal Metastases By Stage and Product Type
• Leptomeningeal Metastases Assessment by Route of Administration
• Leptomeningeal Metastases By Stage and Route of Administration
• Leptomeningeal Metastases Assessment by Molecule Type
• Leptomeningeal Metastases by Stage and Molecule Type

DelveInsight’s Leptomeningeal Metastases Report covers around 5+ products under different phases of clinical development like-

• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Leptomeningeal Metastases product details are provided in the report. Download the Leptomeningeal Metastases pipeline report to learn more about the emerging Leptomeningeal Metastases therapies- Leptomeningeal Metastases Therapeutic Assessment

Leptomeningeal Metastases Pipeline Analysis:

The Leptomeningeal Metastases pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Leptomeningeal Metastases with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Leptomeningeal Metastases Treatment.
• Leptomeningeal Metastases key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Leptomeningeal Metastases Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Leptomeningeal Metastases market.

Download Sample PDF Report to know more about Leptomeningeal Metastases drugs and therapies- Leptomeningeal Metastases Clinical Trials and FDA Approvals

Scope of Leptomeningeal Metastases Pipeline Drug Insight    

• Coverage: Global
• Key Leptomeningeal Metastases Companies: Plus Therapeutics, AstraZeneca, Angiochem, Y-mAbs Therapeutics, TYK Medicines, Inc, Seagen Inc., Pfizer, Genentech, Inc., Angiochem Inc, Daiichi Sankyo, Inc., and others.
• Key Leptomeningeal Metastases Therapies: Rhenium-186 NanoLiposome (186RNL), AZD1390, Paclitaxel trevatide (ANG1005), Omburtamab, and others.
• Leptomeningeal Metastases Therapeutic Assessment: Leptomeningeal Metastases current marketed and Leptomeningeal Metastases emerging therapies
• Leptomeningeal Metastases Market Dynamics: Leptomeningeal Metastases market drivers and Leptomeningeal Metastases market barriers 

Request for Sample PDF Report for Leptomeningeal Metastases Pipeline Assessment and clinical trials – Leptomeningeal Metastases Drugs and Therapies

Table of Contents

1. Leptomeningeal Metastases Report Introduction

2. Leptomeningeal Metastases Executive Summary

3. Leptomeningeal Metastases Overview             

4. Leptomeningeal Metastases- Analytical Perspective In-depth Commercial Assessment

5. Leptomeningeal Metastases Pipeline Therapeutics

6. Leptomeningeal Metastases Late Stage Products (Phase II/III)

7. Leptomeningeal Metastases Mid Stage Products (Phase II)

8. Leptomeningeal Metastases Early Stage Products (Phase I)

9. Leptomeningeal Metastases Preclinical Stage Products

10. Leptomeningeal Metastases Therapeutics Assessment

11. Leptomeningeal Metastases Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Leptomeningeal Metastases Companies

14. Leptomeningeal Metastases Key Products

15. Leptomeningeal Metastases Unmet Needs

16 . Leptomeningeal Metastases Market Drivers and Barriers

17. Leptomeningeal Metastases Future Perspectives and Conclusion

18. Leptomeningeal Metastases Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Ankit Nigam
Email: Send Email
Phone: +14699457679
Address:304 S. Jones Blvd #2432, Las Vegas NV 89107
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com/asco-conference-coverage

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“Major Depressive Disorder Clinical Trials”

(Albany, USA) DelveInsight’s, “Major Depressive Disorder Pipeline Insight” report provides comprehensive insights about 75+ companies and 75+ pipeline drugs in the Major Depressive Disorder pipeline landscape. It covers the Major Depressive Disorder pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Major Depressive Disorder pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Request a sample and discover the recent advances in Major Depressive Disorder Treatment Drugs @ Major Depressive Disorder Pipeline Report

Key Takeaways from the Major Depressive Disorder Pipeline Report

• DelveInsight’s Major Depressive Disorder pipeline report depicts a robust space with 75+ active players working to develop 75+ pipeline therapies for Major Depressive Disorder treatment.
• The leading companies working in the Major Depressive Disorder Market include GH Research, Praxis Precision Medicines, AbbVie, Gedeon Richter, Intra-Cellular Therapies, Bristol-Myers Squibb, Relmada Therapeutics, SAGE Therapeutics, Janssen Research & Development, Minerva Neurosciences, Takeda, Neurocrine Biosciences, Pherin Pharmaceuticals, and others.
• Promising Major Depressive Disorder Pipeline Therapies in the various stages of development include Brexpiprazole, Desvenlafaxine Succinate Sustained-Release 10mg, Cariprazine, Antidepressant Therapy (ADT), and others.
• On December 2023, Cybin IRL Limited announced a study of Phase 1 & 2 clinical trials for CYB003. The purpose of this study is to determine the safety and tolerability of ascending oral doses of CYB003 in healthy participants with and without major depressive disorder (MDD).
• On November 2023, Neumora Therapeutics Inc. announced a study of Phase 3 clinical trials for NMRA 335140. This is a randomized, double blind, placebo controlled, multicenter study to evaluate the effects of NMRA 335140 (formerly BTRX 335140) on symptoms of depression in participants with Major Depressive Disorder (MDD). The study design consists of a Screening Period (up to 28 days), and a 6-week Treatment Period (during which participants will receive either NMRA 335140 or placebo). At the completion of the 6-week Treatment Period, participants who complete the study, provide informed consent, and meet the eligibility criteria may enter an extension study (NMRA 335140 501).
• On October 2023, Neumora Therapeutics Inc. announced a study of phase 3 clinical trials for NMRA 335140. This is a randomized, double blind, placebo controlled, multicenter study to evaluate the effects of NMRA 335140 (formerly BTRX 335140) on symptoms of depression in participants with Major Depressive Disorder (MDD). The study design consists of a Screening Period (up to 28 days), and a 6-week Treatment Period (during which participants will receive either NMRA 335140 or placebo). At the completion of the 6-week Treatment Period, participants who complete the study, provide informed consent, and meet the eligibility criteria may enter an extension study (NMRA 335140 501).
• On October 2023, Intra-Cellular Therapies Inc. announced a study of Phase 3 clinical trials of Lumateperone. This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) who have an inadequate response to ongoing ADT.

In the Major Depressive Disorder pipeline report, a detailed description of the drug is given which includes the mechanism of action of the drug, Major Depressive Disorder clinical trials studies, NDA approvals (if any), and product development activities comprising the technology, Major Depressive Disorder collaborations, licensing, mergers and acquisition, funding, designations and other product-related details.

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Major Depressive Disorder Overview

Major depressive disorder (MDD) is a common and serious mental health condition characterized by persistent feelings of sadness, loss of interest or pleasure in most activities, and a variety of emotional and physical problems. It affects daily functioning and can significantly impair a person’s quality of life.

Symptoms of Major depressive disorder include depressed mood, fatigue, changes in appetite and sleep patterns, difficulty concentrating, feelings of worthlessness or excessive guilt, and recurrent thoughts of death or suicide. To be diagnosed with Major depressive disorder, these symptoms must be present most of the day, nearly every day, for at least two weeks

The exact cause of Major depressive disorder is unknown, but it is believed to result from a combination of genetic, biological, environmental, and psychological factors. Neurotransmitter imbalances, hormonal changes, and stressful life events are among the contributing factors.

Major depressive disorder Diagnosis is based on clinical evaluation, patient history, and standardized assessment tools. Treatment typically involves a combination of medication, such as antidepressants, and psychotherapy, such as cognitive-behavioral therapy (CBT). Lifestyle changes, including regular exercise, a healthy diet, and adequate sleep, can also help manage symptoms.

Early intervention and consistent treatment are crucial for improving outcomes and preventing recurrence. Ongoing research aims to better understand the underlying mechanisms of Major depressive disorder and develop more effective treatments.

Find out more about Major Depressive Disorder Therapeutics Assessment @ Major Depressive Disorder Preclinical and Discovery Stage Products

Major Depressive Disorder Emerging Drugs Profile

• SAGE-217: Sage Therapeutics
• REL-1017: Relmada Therapeutics, Inc
• Seltorexant: Minerva Sciences
• SP-624: Sirtsei Pharmaceuticals, Inc.
• SPL026: Small Pharma
• PDC-1421: BioLite Inc

Major Depressive Disorder Pipeline Therapeutics Assessment

There are approx. 75+ key companies which are developing the Major Depressive Disorder therapies. The Major Depressive Disorder companies which have their Major Depressive Disorder drug candidates in the most advanced stage, i.e. Preregistration include SAGE Therapeutics.

DelveInsight’s Major Depressive Disorder pipeline report covers around 75+ products under different phases of clinical development like

• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Major Depressive Disorder pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

• Oral
• Subcutaneous
• Intravenous
• Intramuscular

Major Depressive Disorder Products have been categorized under various Molecule types such as

• Specific Antibody
• Peptides
• Small molecule
• Gene therapy

Learn more about the emerging Major Depressive Disorder Pipeline Therapies @ Major Depressive Disorder Clinical Trials Assessment

Scope of the Major Depressive Disorder Pipeline Report

• Coverage- Global
• Major Depressive Disorder Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Major Depressive Disorder Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Major Depressive Disorder Companies- GH Research, Praxis Precision Medicines, AbbVie, Gedeon Richter, Intra-Cellular Therapies, Bristol-Myers Squibb, Relmada Therapeutics, SAGE Therapeutics, Janssen Research & Development, Minerva Neurosciences, Takeda, Neurocrine Biosciences, Pherin Pharmaceuticals, and others.
• Major Depressive Disorder Pipeline Therapies- Brexpiprazole, Desvenlafaxine Succinate Sustained-Release 10mg, Cariprazine, Antidepressant Therapy (ADT), and others.

Dive deep into rich insights for new drugs for Major Depressive Disorder Treatment, Visit @ Major Depressive Disorder Treatment Market

Table of Content

1. Introduction
2. Executive Summary
3. Major Depressive Disorder: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Major Depressive Disorder – DelveInsight’s Analytical Perspective
7. Late Stage Products (Preregistration)
8. SAGE-217: Sage Therapeutics
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. SP-624: Sirtsei Pharmaceuticals, Inc.
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I/II)
14. SPL026: Small Pharma
15. Drug profiles in the detailed report…..
16. Preclinical Stage Products
17. Drug Name: Company name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Major Depressive Disorder Key Companies
21. Major Depressive Disorder Key Products
22. Major Depressive Disorder- Unmet Needs
23. Major Depressive Disorder- Market Drivers and Barriers
24. Major Depressive Disorder- Future Perspectives and Conclusion
25. Major Depressive Disorder Analyst Views
26. Major Depressive Disorder Key Companies
27. Appendix

About DelveInsight

DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Ankit Nigam
Email: Send Email
Phone: +14699457679
Address:304 S. Jones Blvd #2432, Las Vegas NV 89107
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com/consulting/conference-coverage-services

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“Open Angle Glaucoma Pipeline”

(Las Vegas, Nevada, United States) As per DelveInsight’s assessment, globally, Open Angle Glaucoma pipeline constitutes 18+ key companies continuously working towards developing 20+ Open Angle Glaucoma treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

“Open Angle Glaucoma Pipeline Insight, 2024″ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Open Angle Glaucoma Market.

The Open Angle Glaucoma Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Request for Sample Report here @ Open Angle Glaucoma Pipeline Outlook

Some of the key takeaways from the Open Angle Glaucoma Pipeline Report:

• Open Angle Glaucoma Companies across the globe are diligently working toward developing novel Open Angle Glaucoma treatment therapies with a considerable amount of success over the years. 
• Open Angle Glaucoma companies working in the treatment market are Nicox Ophthalmics, Betaliq, Inc., Qlaris Bio, Aerpio Pharmaceuticals, Theratocular Biotek, PolyActiva Pty Ltd., Whitecap Biosciences, JeniVision, EMS and others, are developing therapies for the Open Angle Glaucoma treatment 
• Emerging Open Angle Glaucoma therapies such as TO-O-1001, BTQ-1902, NCX 470, and others are expected to have a significant impact on the Open Angle Glaucoma market in the coming years.
• In March 2024, MediPrint® Ophthalmics Announces Successful Completion of Its Phase 2b Glaucoma Clinical Study with Positive Results.
• In February 2024, Skye Bioscience Completes Enrollment of Phase 2a Clinical Trial of SBI-100 Ophthalmic Emulsion in Glaucoma and Ocular Hypertension
• ASCRS 2024: Phase 2 trial of travoprost intracameral implant in open-angle glaucoma or ocular hypertension

Open Angle Glaucoma Overview

Open-angle glaucoma is a chronic eye condition and the most common form of glaucoma, accounting for about 90% of all cases. It is characterized by a gradual increase in intraocular pressure (IOP) due to improper drainage of the aqueous humor, the fluid that nourishes the eye. This increased pressure can damage the optic nerve, leading to progressive and irreversible vision loss if left untreated.

In open-angle glaucoma, the drainage angle formed by the cornea and iris remains open, but the trabecular meshwork, through which the fluid drains, becomes less efficient over time. This leads to a slow buildup of pressure within the eye. The condition is often asymptomatic in its early stages, making regular eye exams crucial for early detection and management.

Risk factors for open-angle glaucoma include age (typically affecting those over 40), a family history of glaucoma, high IOP, certain medical conditions like diabetes and hypertension, and being of African, Hispanic, or Asian descent.

Symptoms, when they do occur, can include peripheral vision loss, which may go unnoticed until significant damage has occurred. Treatment options aim to lower IOP and include medications (eye drops), laser therapy, and surgical procedures. Early diagnosis and consistent management are vital to preserving vision and preventing further optic nerve damage. Regular eye check-ups are essential, especially for those at higher risk.

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Open Angle Glaucoma Route of Administration

Open Angle Glaucoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

• Intravenous
• Subcutaneous
• Oral
• Intramuscular

Open Angle Glaucoma Molecule Type

Open Angle Glaucoma Products have been categorized under various Molecule types, such as

• Monoclonal antibody
• Small molecule
• Peptide

Open Angle Glaucoma Pipeline Therapeutics Assessment

• Open Angle Glaucoma Assessment by Product Type
• Open Angle Glaucoma By Stage and Product Type
• Open Angle Glaucoma Assessment by Route of Administration
• Open Angle Glaucoma By Stage and Route of Administration
• Open Angle Glaucoma Assessment by Molecule Type
• Open Angle Glaucoma by Stage and Molecule Type

DelveInsight’s Open Angle Glaucoma Report covers around 20+ products under different phases of clinical development like-

• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Open Angle Glaucoma product details are provided in the report. Download the Open Angle Glaucoma pipeline report to learn more about the emerging Open Angle Glaucoma therapies- Open Angle Glaucoma Drugs and Therapies

Open Angle Glaucoma Pipeline Analysis:

The Open Angle Glaucoma pipeline report provides insights into 

• The report provides detailed insights about companies that are developing therapies for the treatment of Open Angle Glaucoma with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Open Angle Glaucoma Treatment.
• Open Angle Glaucoma key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Open Angle Glaucoma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Open Angle Glaucoma market.

Download Sample PDF Report to know more about Open Angle Glaucoma drugs and therapies- Open Angle Glaucoma Clinical Trials and FDA Approvals

Scope of Open Angle Glaucoma Pipeline Drug Insight    

• Coverage: Global
• Key Open Angle Glaucoma Companies: Nicox Ophthalmics, Betaliq, Inc., Qlaris Bio, Aerpio Pharmaceuticals, Theratocular Biotek, PolyActiva Pty Ltd., Whitecap Biosciences, JeniVision, EMS and others.
• Key Open Angle Glaucoma Therapies: TO-O-1001, BTQ-1902, NCX 470, and others.
• Open Angle Glaucoma Therapeutic Assessment: Open Angle Glaucoma current marketed and Open Angle Glaucoma emerging therapies
• Open Angle Glaucoma Market Dynamics: Open Angle Glaucoma market drivers and Open Angle Glaucoma market barriers 

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Table of Contents

1. Open Angle Glaucoma Report Introduction

2. Open Angle Glaucoma Executive Summary

3. Open Angle Glaucoma Overview 

4. Open Angle Glaucoma- Analytical Perspective In-depth Commercial Assessment

5. Open Angle Glaucoma Pipeline Therapeutics

6. Open Angle Glaucoma Late Stage Products (Phase II/III)

7. Open Angle Glaucoma Mid Stage Products (Phase II)

8. Open Angle Glaucoma Early Stage Products (Phase I)

9. Open Angle Glaucoma Preclinical Stage Products

10. Open Angle Glaucoma Therapeutics Assessment

11. Open Angle Glaucoma Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. Open Angle Glaucoma Companies

14. Open Angle Glaucoma Key Products

15. Open Angle Glaucoma Unmet Needs

16 . Open Angle Glaucoma Market Drivers and Barriers

17. Open Angle Glaucoma Future Perspectives and Conclusion

18. Open Angle Glaucoma Analyst Views

19. Appendix

20. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Ankit Nigam
Email: Send Email
Phone: +14699457679
Address:304 S. Jones Blvd #2432, Las Vegas NV 89107
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com/asco-conference-coverage

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Open Angle Glaucoma Pipeline Analysis 2024: FDA Approvals, Clinical Trials, Therapies, Mechanism of Action, Route of Administration by DelveInsight

“Head and Neck Cancer Clinical Trials”

(Albany, USA) DelveInsight’s ‘Head and Neck Cancer Pipeline Insight 2024’ report provides comprehensive global coverage of available, marketed, and pipeline head and neck cancer therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the head and neck cancer pipeline domain.

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Key Takeaways from the Head and Neck Cancer Pipeline Report

• DelveInsight’s head and neck cancer pipeline report depicts a robust space with 100+ active players working to develop 120+ pipeline therapies for head and neck cancer treatment. 
• Key head and neck cancer companies such as Innate Pharma, GlaxoSmithKline, Debiopharm, Checkpoint Therapeutics, Quadriga BioSciences, Palleon Pharmaceuticals, Klus Pharma, Bicycle Therapeutics, CSPC ZhongQi Pharmaceutical Technology, Memgen, I-Mab Biopharma, Intensity Therapeutics, Wellmaker Bio, SN BioScience, Carisma Therapeutics, Genentech, Pionyr Immunotherapeutics, Palleon Pharmaceuticals, SN BioScience, Bicycle Therapeutics, Inhibrx, Celldex Therapeutics, Carisma Therapeutics Inc, BioAtla, Jacobio Pharmaceuticals, Compugen, GeoVax, CytomX Therapeutics, PNP Therapeutics, Galectin Therapeutics, Cyteir Therapeutics, Merck KGaA, Boehringer Ingelheim, Transgene, iTeos Therapeutics SA,  IntraGel Therapeutics, Incyte Corporation, Cue Biopharma, Rubius Therapeutics, Alkermes, Corregene Biotechnology, NanoCarrier, Kura Oncology, Betta Pharmaceuticals, Arcus Biosciences, Taiho Pharmaceutical, Astex Pharmaceuticals, Bayer HealthCare, Roche, Vaccinex, Pfizer, BioNTech,  Purple Biotech, Novartis Oncology, Macrogenics, Aveta Biomics, Cellectar Biosciences, Nanobiotix, Nektar Therapeutics, Istari Oncology, Nanobiotix, Aspyrian Therapeutics, and others are evaluating new head and neck cancer drugs to improve the treatment landscape.
• Promising head and neck cancer pipeline therapies such as Niraparib, Xevinapant, , CK-301, QBS10072S, A166, E-602, BT5528, RAPA-201, Mitoxantrone Hydrochloride, MEM-288, TJ004309, SNB-101, INT230-6, CT-0508, WM-S1-030, CDX-1140, PY159, MCLA-129, INBRX-106, Autogene cevumeran, JAB-3068, CAB-ROR2-ADC, CX-2029, Ad/PNP, COM701, Eftilagimod alpha, CYT-0851, GR-MD-02, TG4050, BI 765063, TumoCure, EOS-448, Epacadostat, RTX-321, CUE-101, ALKS 4230, CRTE7A2-01, NC-6004, Tipifarnib, MCLA-129, Zimberelimab, HLX10 Plus HLX07, Tolinapant, BAY1905254, OSI-774, VX15/2503, Palbociclib, Olaparib, NT219, BNT113, Buparlisib, Retifanlimab, Avelumab, APG-157, CLR 131, NBTXR3, Evorpacept, Dostarlimab, NKTR-214, IK-175, Lerapolturev, NBTXR3, Gedeptin, RM-1995, Atezolizumab and others are under different phases of head and neck cancer clinical trials.
• In September 2022, NANOBIOTIX announced randomization of the first patient in Asia in NANORAY-312, a global Phase III registrational trial evaluating NBTXR3 for the treatment of elderly patients with locally advanced head and neck squamous cell carcinoma who are ineligible for platinum-based chemotherapy.
• In August 2022, Genexine announced the dosing of the first patient in Phase II clinical trial using triple combination therapy in patients with recurrent/metastatic HNSCC. The combination therapy consists of two of Genexine’s proprietary drugs, GX-188E (a first-in-class therapeutic DNA vaccine), GX-I7 (a first-in-class long-acting interleukin 7), and Opdivo (nivolumab), a marketed PD-1 immune checkpoint inhibitor.
• In May 2022, Calliditas announced that it had initiated Phase II head and neck cancer therapy trial. The trial will analyze the impact of setanaxib plus pembrolizumab in patients with CAF-density tumors. Calliditas Therapeutics has randomized the first subject in the proof-of-concept Phase II clinical trial of setanaxib (GKT831) in individuals with squamous cell carcinoma of the head and neck (SCCHN).

Request a sample and discover the recent advances in head and neck cancer treatment drugs @ Head and Neck Cancer Treatment Market

Head and Neck Cancer Overview

Head and neck cancer is a collective term for several different types of cancer. Cancers of the head and neck are classified according to where they begin. The mouth (oral cavity), throat (pharynx), voice box (larynx), sinuses and nose cavity, and salivary glands are all included. Squamous cell carcinoma of the head and neck is the most common type of head and neck cancer (HNSCCA). The majority of HNSCCA begins in the layer of flat cells (the epithelium) that lines the upper aerodigestive tract structures such as the mouth, throat, and voice box.

Head and neck cancer symptoms include a lump in the neck or a sore in the mouth or throat that does not heal, a persistent sore throat, difficulty swallowing, and a change or hoarseness in voice; however, these head and neck cancer symptoms can also be caused by other, less severe illnesses.

For head and neck diagnosis, physical examination/blood and urine tests, endoscopy, biopsy, biomarker testing of the tumor, X-ray/barium swallow, panoramic radiograph, ultrasound, magnetic resonance imaging, bone scan, and other tests are used.

Learn more about the emerging head and neck cancer pipeline therapies @ Head and Neck Cancer Drugs and Therapies

Head and Neck Cancer Therapeutics Assessment

Over 100+ prominent companies are actively involved in the development of therapies for Head and Neck cancer. Among these, certain companies have positioned themselves at the forefront by advancing their Head and Neck cancer drug candidates to the most advanced stage, namely Phase III.

For further information on the head and neck cancer pipeline therapeutics, reach out @ Head and Neck Cancer Drugs and Therapeutic Assessment

Scope of the Head and Neck Cancer Pipeline Report 

• Coverage: Global 
• Therapeutic Assessment By Product Type: Mono, Combination, Mono/Combination
• Therapeutic Assessment By Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Therapeutics Assessment By Route of Administration: Inhalation, Intranasal, Intravenous, Oral, Parenteral, Subcutaneous
• Therapeutics Assessment By Molecule Type: Antibody, Antisense oligonucleotides, Immunotherapy, Monoclonal antibody, Peptides, Protein, Recombinant protein, Small molecule, Stem cell, Vaccine
• Therapeutics Assessment By Mechanism of Action: Antibody-dependent cell cytotoxicity, NK cell lectin-like receptor subfamily C antagonists, Poly(ADP-ribose) polymerase 1 inhibitors, Poly(ADP-ribose) polymerase 2 inhibitors, Inhibitor of apoptosis protein inhibitors, T lymphocyte stimulants, Aryl hydrocarbon receptor antagonists, DNA topoisomerase I inhibitors; CD40 ligand expression stimulants; Cell death stimulants; Immunologic cytotoxicity, Galectin 3 inhibitors, CD40 antigen stimulants
• Key Head and Neck Cancer Companies: Innate Pharma, GlaxoSmithKline, Debiopharm, Checkpoint Therapeutics, Quadriga BioSciences, Palleon Pharmaceuticals, Klus Pharma, Bicycle Therapeutics, CSPC ZhongQi Pharmaceutical Technology, Memgen, I-Mab Biopharma, Intensity Therapeutics, Wellmaker Bio, SN BioScience, Carisma Therapeutics, Genentech, Pionyr Immunotherapeutics, Palleon Pharmaceuticals, SN BioScience, Bicycle Therapeutics, Inhibrx, Celldex Therapeutics, Carisma Therapeutics Inc, BioAtla, Jacobio Pharmaceuticals, Compugen, GeoVax, CytomX Therapeutics, PNP Therapeutics, Galectin Therapeutics, Cyteir Therapeutics, Merck KGaA, Boehringer Ingelheim, Transgene, iTeos Therapeutics SA,  IntraGel Therapeutics, Incyte Corporation, Cue Biopharma, Rubius Therapeutics, Alkermes, Corregene Biotechnology, NanoCarrier, Kura Oncology, Betta Pharmaceuticals, Arcus Biosciences, Taiho Pharmaceutical, Astex Pharmaceuticals, Bayer HealthCare, Roche, Vaccinex, Pfizer, BioNTech,  Purple Biotech, Novartis Oncology, Macrogenics, Aveta Biomics, Cellectar Biosciences, Nanobiotix, Nektar Therapeutics, Istari Oncology, Nanobiotix, Aspyrian Therapeutics and others.
• Key Head and Neck Cancer Pipeline Therapies: Niraparib, Xevinapant, , CK-301, QBS10072S, A166, E-602, BT5528, RAPA-201, Mitoxantrone Hydrochloride, MEM-288, TJ004309, SNB-101, INT230-6, CT-0508, WM-S1-030, CDX-1140, PY159, MCLA-129, INBRX-106, Autogene cevumeran, JAB-3068, CAB-ROR2-ADC, CX-2029, Ad/PNP, COM701, Eftilagimod alpha, CYT-0851, GR-MD-02, TG4050, BI 765063, TumoCure, EOS-448, Epacadostat, RTX-321, CUE-101, ALKS 4230, CRTE7A2-01, NC-6004, Tipifarnib, MCLA-129, Zimberelimab, HLX10 Plus HLX07, Tolinapant, BAY1905254, OSI-774, VX15/2503, Palbociclib, Olaparib, NT219, BNT113, Buparlisib, Retifanlimab, Avelumab, APG-157, CLR 131, NBTXR3, Evorpacept, Dostarlimab, NKTR-214, IK-175, Lerapolturev, NBTXR3, Gedeptin, RM-1995, Atezolizuma, and others.

Dive deep into rich insights for new drugs for head and neck cancer treatment, visit @ Head and Neck Cancer Clinical Trials and FDA Approvals

Table of Contents

1. Report Introduction
2. Executive Summary
3. Head and Neck Cancer Current Treatment Patterns
4. Head and Neck Cancer – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Head and Neck Cancer Late-Stage Products (Phase-III)
7. Head and Neck Cancer Mid-Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Head and Neck Cancer Discontinued Products
13. Head and Neck Cancer Product Profiles
14. Head and Neck Cancer Companies
15. Head and Neck Cancer Drugs
16. Dormant and Discontinued Products
17. Head and Neck Cancer Unmet Needs
18. Head and Neck Cancer Future Perspectives
19. Head and Neck Cancer Analyst Review
20. Appendix
21. Report Methodology

About DelveInsight

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