(Albany, USA) DelveInsight’s “Autosomal Dominant Polycystic Kidney Disease Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the Autosomal Dominant Polycystic Kidney Disease, historical and forecasted epidemiology as well as the Autosomal Dominant Polycystic Kidney Disease market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.
To Know in detail about the Autosomal Dominant Polycystic Kidney Disease market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Autosomal Dominant Polycystic Kidney Disease Market Forecast
Some of the key facts of the Autosomal Dominant Polycystic Kidney Disease Market Report:
- The Autosomal Dominant Polycystic Kidney Disease market size was valued approximately ~USD 1,476 million in 2023 and is anticipated to grow with a significant CAGR during the study period (2020-2034)
- In 2023, the US market was valued at around USD 889.8 million. This figure is expected to shift with the introduction of emerging therapies throughout the forecast period (2024-2034).
- In 2023, the combined market size of EU4 and the UK was approximately USD 7,395 million, representing nearly 39.4% of the total 7MM market.
- In the EU4 and the UK, the UK had the largest autosomal dominant polycystic kidney disease market size at around USD 72.5 million, followed by France with approximately USD 65.6 million and Spain with USD 29.4 million. These figures are projected to shift by 2034.
- In 2023, Japan represented about 26% of the total Autosomal Dominant Polycystic Kidney Disease market across the 7MM. These proportions are expected to shift by 2034.
- According to DelveInsight’s analysis, the total diagnosed prevalent cases of autosomal dominant polycystic kidney disease in the 7MM were approximately 194,251 in 2023. This number is expected to change during the forecast period from 2024 to 2034.
- In 2023, the US reported approximately 144,697 diagnosed prevalent cases of autosomal dominant polycystic kidney disease.
- In 2023, the UK reported the highest number of autosomal dominant polycystic kidney disease diagnosed prevalent cases among the EU4 and the UK, with approximately 68,138 cases, followed by France with 61,676 cases. Italy had the lowest, with nearly 16,476 cases.
- Key Autosomal Dominant Polycystic Kidney Disease Companies: Otsuka America Pharmaceuticals, Vertex Pharmaceuticals, Pfizer, Otsuka Pharma, Palladio Biosciences, Novartis Pharma, XORTX Therapeutic, ReataPharmaceuticals, Kyowa Kirin, Sanofi, Galapagos NV, Janssen Pharmaceuticals, Regulus Therapeutics, and others
- Key Autosomal Dominant Polycystic Kidney Disease Therapies: JYNARQUE/ JINARC/SAMSCA (tolvaptan), VX-407, Bosutinib, Tolvaptan, Lixivaptan, Everolimus, OPC-41061, Rapamune, XRx-008, Bardoxolonemethyl, Tesevatinib/KD019, GLPG2737, JNJ-0237/AT-20494, RGLS8429, and others
- The ADPKD epidemiology based on mutation-specific cases analyzed that the mutation-specific distribution of the disease suggests a higher prevalence of ADPKD due to mutation in PKD1 gene than in PKD2 gene
- The Autosomal Dominant Polycystic Kidney Disease market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Autosomal Dominant Polycystic Kidney Disease pipeline products will significantly revolutionize the Autosomal Dominant Polycystic Kidney Disease market dynamics.
Autosomal Dominant Polycystic Kidney Disease Overview
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disorder characterized by the growth of numerous fluid-filled cysts in the kidneys. It is caused by mutations in either the PKD1 or PKD2 genes, which disrupt normal kidney cell function. This leads to progressive kidney enlargement, structural damage, and eventual loss of kidney function.
Symptoms typically appear in adulthood, although some individuals remain asymptomatic for years. Common signs include high blood pressure, back or flank pain, blood in the urine (hematuria), recurrent urinary tract infections, and kidney stones. Over time, the disease can progress to chronic kidney disease (CKD) and end-stage renal disease (ESRD), necessitating dialysis or kidney transplantation.
ADPKD can also cause extrarenal complications, including liver cysts, aneurysms in brain blood vessels, heart valve abnormalities, and hernias. Diagnosis is often confirmed through imaging studies like ultrasound, CT, or MRI, and genetic testing may be utilized for high-risk individuals.
Treatment focuses on managing symptoms and slowing disease progression. Blood pressure control, dietary modifications, and pain management are essential. Medications such as tolvaptan may be prescribed to delay kidney function decline. Regular monitoring and early intervention are crucial to improving quality of life for individuals with ADPKD.
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Autosomal Dominant Polycystic Kidney Disease Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.
Autosomal Dominant Polycystic Kidney Disease Epidemiology Segmentation:
The Autosomal Dominant Polycystic Kidney Disease market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into:
- Total Prevalence of Autosomal Dominant Polycystic Kidney Disease
- Prevalent Cases of Autosomal Dominant Polycystic Kidney Disease by severity
- Gender-specific Prevalence of Autosomal Dominant Polycystic Kidney Disease
- Diagnosed Cases of Episodic and Chronic Autosomal Dominant Polycystic Kidney Disease
Download the report to understand which factors are driving Autosomal Dominant Polycystic Kidney Disease epidemiology trends @ Autosomal Dominant Polycystic Kidney Disease Epidemiology Forecast
Autosomal Dominant Polycystic Kidney Disease Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Autosomal Dominant Polycystic Kidney Disease market or expected to get launched during the study period. The analysis covers Autosomal Dominant Polycystic Kidney Disease market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Autosomal Dominant Polycystic Kidney Disease Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
Autosomal Dominant Polycystic Kidney Disease Therapies and Key Companies
- JYNARQUE/ JINARC/SAMSCA (tolvaptan): Otsuka America Pharmaceuticals
- VX-407: Vertex Pharmaceuticals
- Bosutinib: Pfizer
- Tolvaptan: Otsuka Pharma
- Lixivaptan: Palladio Biosciences
- Everolimus: Novartis Pharma
- OPC-41061: Otsuka Pharma
- Rapamune: Pfizer
- XRx-008: XORTX Therapeutic
- Bardoxolonemethyl: ReataPharmaceuticals/ Kyowa Kirin
- Tesevatinib/KD019: Sanofi
- GLPG2737: Galapagos NV
- JNJ-0237/AT-20494: Janssen Pharmaceuticals
- RGLS8429: Regulus Therapeutics
Discover more about therapies set to grab major Autosomal Dominant Polycystic Kidney Disease market share @ Autosomal Dominant Polycystic Kidney Disease Treatment Landscape
Autosomal Dominant Polycystic Kidney Disease Market Drivers
- Technological advances in diagnostic procedures due to an increasing focus on early diagnosis has reduced undiagnosed cases, thus persistent rising cases of diagnosed ADPKD offer opportunities to companies to launch new therapies in the market.
- Advances are being made in unravelling the genetic origins of ADPKD, in non-invasive monitoring and in predicting disease progression that will help in better disease management
Autosomal Dominant Polycystic Kidney Disease Market Opportunities
- Pre-symptomatic diagnosis and their application in the care and management of individuals at risk for ADPKD.
- Identification of biomarkers for early detection of ADPKD patients at high risk for progression will help better manage ADPKD patients and prevent their progression.
Scope of the Autosomal Dominant Polycystic Kidney Disease Market Report
- Study Period: 2020–2034
- Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
- Key Autosomal Dominant Polycystic Kidney Disease Companies: Otsuka America Pharmaceuticals, Vertex Pharmaceuticals, Pfizer, Otsuka Pharma, Palladio Biosciences, Novartis Pharma, XORTX Therapeutic, ReataPharmaceuticals, Kyowa Kirin, Sanofi, Galapagos NV, Janssen Pharmaceuticals, Regulus Therapeutics, and others
- Key Autosomal Dominant Polycystic Kidney Disease Therapies: JYNARQUE/ JINARC/SAMSCA (tolvaptan), VX-407, Bosutinib, Tolvaptan, Lixivaptan, Everolimus, OPC-41061, Rapamune, XRx-008, Bardoxolonemethyl, Tesevatinib/KD019, GLPG2737, JNJ-0237/AT-20494, RGLS8429, and others
- Autosomal Dominant Polycystic Kidney Disease Therapeutic Assessment: Autosomal Dominant Polycystic Kidney Disease current marketed and Autosomal Dominant Polycystic Kidney Disease emerging therapies
- Autosomal Dominant Polycystic Kidney Disease Market Dynamics: Autosomal Dominant Polycystic Kidney Disease market drivers and Autosomal Dominant Polycystic Kidney Disease market barriers
- Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies
- Autosomal Dominant Polycystic Kidney Disease Unmet Needs, KOL’s views, Analyst’s views, Autosomal Dominant Polycystic Kidney Disease Market Access and Reimbursement
To know more about Autosomal Dominant Polycystic Kidney Disease companies working in the treatment market, visit @ Autosomal Dominant Polycystic Kidney Disease Clinical Trials and Therapeutic Assessment
Table of Contents
1. Autosomal Dominant Polycystic Kidney Disease Market Report Introduction
2. Executive Summary for Autosomal Dominant Polycystic Kidney Disease
3. SWOT analysis of Autosomal Dominant Polycystic Kidney Disease
4. Autosomal Dominant Polycystic Kidney Disease Patient Share (%) Overview at a Glance
5. Autosomal Dominant Polycystic Kidney Disease Market Overview at a Glance
6. Autosomal Dominant Polycystic Kidney Disease Disease Background and Overview
7. Autosomal Dominant Polycystic Kidney Disease Epidemiology and Patient Population
8. Country-Specific Patient Population of Autosomal Dominant Polycystic Kidney Disease
9. Autosomal Dominant Polycystic Kidney Disease Current Treatment and Medical Practices
10. Autosomal Dominant Polycystic Kidney Disease Unmet Needs
11. Autosomal Dominant Polycystic Kidney Disease Emerging Therapies
12. Autosomal Dominant Polycystic Kidney Disease Market Outlook
13. Country-Wise Autosomal Dominant Polycystic Kidney Disease Market Analysis (2020–2034)
14. Autosomal Dominant Polycystic Kidney Disease Market Access and Reimbursement of Therapies
15. Autosomal Dominant Polycystic Kidney Disease Market Drivers
16. Autosomal Dominant Polycystic Kidney Disease Market Barriers
17. Autosomal Dominant Polycystic Kidney Disease Appendix
18. Autosomal Dominant Polycystic Kidney Disease Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight
About DelveInsight
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It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.
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