NNB Nutrition recently conducted a study demonstrating the inhibiting effects of GlucoVantage® on overweight individuals.
Research details:
Building upon previous studies that have established DHB’s superior blood glucose control effects, NNB Nutrition conducted new research to investigate the impact of GlucoVantage® combined with exercise on mice with high-fat diets, specifically focusing on its ability to inhibit overweight.
To facilitate the study, five different groups of mice were established, two of which were injected with 26mg of GlucoVantage®. The body weight and subcutaneous adipose tissue weight of the mice were evaluated to assess the weight-reducing effects of GlucoVantage®. Additionally, serum biochemical parameters including triglyceride levels, low-density lipoprotein (LDL), and reactive oxygen species (ROS) were analyzed to determine GlucoVantage®’s potential in inhibiting overweight based on serum indexes.
Results:
1. Evaluation of body weight changes:
Figure 1. Body weight change. *P < 0.05, **P < 0.01 compared with HFD (high fat diet) group.
*Exercise mice were acclimated on a motor-driven treadmill and ran at 10 m/min for 30 min per day, and 5 days per week for 8 weeks.
Compared to the high-fat group and other groups, the combination of GlucoVantage® and exercise exhibited significant differences, indicating that GlucoVantage®, either alone or combined with exercise, can effectively inhibit overweight.
2. Evaluation of triglyceride (TG) levels:
Figure 2. Serum lipid metabolism indexes TG *P < 0.05, **P < 0.01 compared with HFD group
Compared to the high-fat group, GlucoVantage® alone or in combination with exercise significantly inhibited triglyceride levels (a risk factor for cardiovascular disease).
3. Evaluation of low-density lipoprotein (LDL) levels:
Figure 3. Serum lipid metabolism indexes LDL *P < 0.05, **P < 0.01 compared with HFD group.
LDL, often called as “bad cholesterol,” exhibited a notable decrease in both the GlucoVantage® and GlucoVantage® combined with exercise groups, as indicated by the study results.
4. Evaluation of reactive oxygen species (ROS):
Figure 4. Serum antioxidant indexes ROS in mice. #P < 0.05 compared with HFD+exercise group.
ROS levels increase significantly during environmental stress and can cause significant damage to cell structures. Figure 4 demonstrates that the combination of GlucoVantage® and exercise contributes to a decrease in ROS content.
Conclusion:
Taking into account the changes in body weight and serum lipid metabolism indexes, the study confirms that GlucoVantage® effectively inhibits the tendency to become overweight. Furthermore, combining GlucoVantage® with exercise enhances this effect.
These compelling findings pave the way for GlucoVantage® as an effective solution to combat overweight and inspire individuals seeking to achieve healthier lifestyle.
About NNB
NNB is the leading ingredient-driven biotech company employing over 100 research scientists from more than 10 countries who study, design, and deliver unique ingredients to the industry to maximize health, augment performance, expand longevity and enhance appearance. NNB fosters partnerships with companies in the fields of nutraceuticals, pharmaceuticals, and medical research.
Media Contact
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Website: https://www.nnbnutrition.com/