(Albany, USA) DelveInsight’s “CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Insights, Epidemiology, and Market Forecast-2034” report delivers an in-depth understanding of CAR T-Cell Therapy for Non-Hodgkin’s lymphoma, historical and forecasted epidemiology as well as the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.
The CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market size from 2020 to 2034, segmented by seven major markets. The Report also covers current CAR T-Cell Therapy for Non-Hodgkin’s lymphoma treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market.
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Some facts of the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Report are:
- According to DelveInsight, CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market size is expected to grow at a decent CAGR by 2034.
- CAR T-Cell Therapy for Non-Hodgkin’s lymphoma companies working in the treatment market are Allogene Therapeutics, Novartis, Miltenyi Biomedicine, Mustang Bio, CRISPR Therapeutics, 2seventy Bio, Imugene, Juno Therapeutics, Caribou Biosciences, and others, are developing therapies for the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma treatment
- Emerging CAR T-Cell Therapy for Non-Hodgkin’s lymphoma therapies such as JCAR017, CB010, and others are expected to have a significant impact on the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market in the coming years.
- BREYANZI is poised to dominate the CAR-T market in NHL in the forthcoming years, with potential approvals anticipated across two indications: CLL/SLL, follicular lymphoma and MCL. Notably, it has already secured approval for DLBCL in 3L+, 2L+ TE, and NTE.
- Novartis is progressing with its additional CD-19 CAR-T therapy, Rapcabtagene autoleucel, with expectations of a significantly reduced turnaround time for availability compared to KYMRIAH.
- Allogene Therapeutics: Developing ALLO-501A, targeting CD19 for relapsed/refractory NHL; clinical trials are ongoing. Preliminary data presented in March 2024 indicate potential effectiveness.
- Novartis: Advancing CTL119 in Phase II trials, focusing on relapsed large B-cell lymphoma. Updated results are expected in June 2024 at the ASCO Annual Meeting.
- Miltenyi Biomedicine: Introduced MACS-iT CAR T-cell therapy in early-stage clinical trials, emphasizing a unique manufacturing process to enhance T-cell quality. Initial findings were presented in February 2024.
- Mustang Bio: Developing MB-106, a Phase I/II therapy targeting CD20 for relapsed/refractory NHL. Interim results were shared in April 2024.
- CRISPR Therapeutics: Working on CTX110, a CRISPR-engineered autologous CAR T-cell therapy targeting CD19 in Phase I trials. Data released in January 2024 shows early promise.
- 2seventy Bio: Conducting ongoing trials on multiple CAR-T candidates, focusing on innovative approaches to enhance efficacy against NHL. Updates are expected mid-2024, with results anticipated at a future conference.
- Imugene: Developing OnCARlytics, an early clinical trial therapy that integrates an oncolytic virus approach to enhance CAR T-cell efficacy. Initial trial data were presented in March 2024.
- Juno Therapeutics (Bristol Myers Squibb): Achieved FDA approval for JCAR017 (Lisocabtagene maraleucel), a CAR T-cell therapy for NHL, in January 2024, marking a significant milestone.
- Caribou Biosciences: Advancing CB010 in early-stage clinical trials, utilizing CRISPR technology to enhance CAR T-cell specificity. Initial trial results are expected by the end of 2024.
- Galapagos NV: Developing GLPG5101 and GLPG5201, both CD19 CAR-T therapies. GLPG5101 is in Phase 1/2, with data presented at the EHA Congress in June 2024. GLPG5201, also in Phase 1/2, focuses on chronic lymphocytic leukemia and Richter transformation, with ongoing updates throughout 2024.
CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Overview
CAR T-Cell Therapy for Non-Hodgkin’s Lymphoma (NHL) is a revolutionary treatment that harnesses the body’s immune system to fight cancer. This advanced therapy involves modifying a patient’s T cells, a type of white blood cell, to express a Chimeric Antigen Receptor (CAR) that targets specific antigens on the surface of lymphoma cells. Once infused back into the patient, these engineered T cells recognize and destroy the cancerous cells.
CAR T-cell therapy has shown remarkable success in treating aggressive and relapsed/refractory forms of NHL, such as diffuse large B-cell lymphoma (DLBCL). Approved therapies, including Yescarta® (axicabtagene ciloleucel) and Kymriah® (tisagenlecleucel), have demonstrated significant response rates, offering hope to patients with limited treatment options.
Despite its promise, CAR T-cell therapy is associated with challenges such as high costs, manufacturing complexities, and potential side effects, including cytokine release syndrome (CRS) and neurotoxicity. However, advancements in CAR design and manufacturing are addressing these limitations.
The ongoing development of CAR T-cell therapies continues to expand their accessibility and effectiveness, establishing them as a cornerstone in the treatment of NHL and a vital component of modern oncology.
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CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market
The CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market trends by analyzing the impact of current CAR T-Cell Therapy for Non-Hodgkin’s lymphoma therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.
This segment gives a thorough detail of the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market in 7MM is expected to witness a major change in the study period 2020-2034.
CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Epidemiology
The CAR T-Cell Therapy for Non-Hodgkin’s lymphoma epidemiology section provides insights into the historical and current CAR T-Cell Therapy for Non-Hodgkin’s lymphoma patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market report also provides the diagnosed patient pool, trends, and assumptions.
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CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Drugs Uptake
This section focuses on the uptake rate of the potential CAR T-Cell Therapy for Non-Hodgkin’s lymphoma drugs recently launched in the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market or expected to be launched in 2020-2034. The analysis covers the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market uptake by drugs, patient uptake by therapies, and sales of each drug.
CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on CAR T-Cell Therapy for Non-Hodgkin’s lymphoma market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Pipeline Development Activities
The CAR T-Cell Therapy for Non-Hodgkin’s lymphoma report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses CAR T-Cell Therapy for Non-Hodgkin’s lymphoma key players involved in developing targeted therapeutics.
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CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Therapeutics Assessment
Major key companies are working proactively in the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Therapeutics market to develop novel therapies which will drive the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma treatment markets in the upcoming years are Allogene Therapeutics, Novartis, Miltenyi Biomedicine, Mustang Bio, CRISPR Therapeutics, 2seventy Bio, Imugene, Juno Therapeutics, Caribou Biosciences, and others.
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CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Report Key Insights
1. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Patient Population
2. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Size and Trends
3. Key Cross Competition in the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market
4. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Dynamics (Key Drivers and Barriers)
5. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Opportunities
6. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Therapeutic Approaches
7. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Pipeline Analysis
8. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market
Table of Contents
1. Key Insights
2. Executive Summary
3. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Competitive Intelligence Analysis
4. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Overview at a Glance
5. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Disease Background and Overview
6. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Patient Journey
7. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Epidemiology and Patient Population
8. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Treatment Algorithm, Current Treatment, and Medical Practices
9. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Unmet Needs
10. Key Endpoints of CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Treatment
11. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Marketed Products
12. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Emerging Therapies
13. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Seven Major Market Analysis
14. Attribute Analysis
15. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Outlook (7 major markets)
16. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Access and Reimbursement Overview
17. KOL Views on the CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market
18. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Drivers
19. CAR T-Cell Therapy for Non-Hodgkin’s lymphoma Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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