DelveInsight’s, “HR Positive/ HER2 Negative Breast Cancer Pipeline Insight 2024” report provides comprehensive insights about 50+ companies and 53+ pipeline drugs in HR Positive/ HER2 Negative Breast Cancer pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the HR+ HER2-ve Breast Cancer Pipeline Report
- In November 2024:- Tolmar Inc.- Phase 3,Single Arm,Open-Label Study Evaluating Ovarian Suppression Following 3 Month Leuprolide Acetate For Injectable Suspension (TOL2506) in Combination With Endocrine Therapy in Premenopausal Subjects With Hormone-Receptor-Positive (HR+),Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer.
- In October 2024:- Novartis Pharmaceuticals- The purpose of this Cohort Treatment Plan is to allow access to alpelisib for patients diagnosed with HR-positive, HER2-negative advanced breast cancer with mutated phosphoinositide 3-kinase who progressed on or after AI treatment. The patient’s Treating Physician should follow the suggested treatment guidelines and comply with all local health authority regulations.
- DelveInsight’s HR+ HER2-ve Breast Cancer pipeline report depicts a robust space with 50+ active players working to develop 53+ pipeline therapies for HR+ HER2-ve Breast Cancer treatment.
- The leading HR+ HER2-ve Breast Cancer Companies such as Regor Therapeutics, Seagen Inc., CytomX Therapeutics, Taizhou EOC Pharma, Chia Tai Tianqing Pharmaceutical Group, AstraZeneca, Daiichi Sankyo, Inc., Tyme, Inc., Context Therapeutics, Eisai Inc., Shanghai Hengrui Pharmaceutical Co., Ltd., Jiangsu Simcere Pharmaceutical Co., Kind Pharmaceuticals, Merus N.V., Atossa Therapeutics, Roche and others.
- Promising HR+ HER2-ve Breast Cancer Therapies such as TQB3616 capsule, NTQ1062 with Fulvestrant, Pembrolizumab, Sacituzumab Govitecan, Dapagliflozin 10Mg Tab, SM-88, VS-6766, Abemaciclib, and others.
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HR+ HER2-ve Breast Cancer Emerging Drugs Profile
- Camizestrant: AstraZeneca
Camizestrant is a potent, next-generation oral SERD and pure ERα antagonist, that has demonstrated anti-cancer activity across a range of preclinical models, including those with ER-activating mutations. The asset has been shown to promising anti-tumour profile when administered alone or in combination with palbociclib and thus, the company is running a Phase III trial for the same.
- Dato-DXd: Daiichi Sankyo, Inc.
Datopotamab deruxtecan (Dato-DXd) is an investigational currently in Phase III for HR-positive, HER2- negative breast cancer. It is a TROP2 directed antibody drug conjugate (ADC) designed using Daiichi Sankyo’s proprietary DXd ADC technology, datopotamab deruxtecan is one of the three lead ADCs in the oncology pipeline of Daiichi Sankyo, and one of the most advanced programs in AstraZeneca’s ADC scientific platform. Datopotamab deruxtecan is comprised of a humanized anti-TROP2 IgG1 monoclonal antibody, developed in collaboration with Sapporo Medical University, attached to a number of topoisomerase I inhibitor payloads, an exatecan derivative, via tetrapeptide-based cleavable linkers.
- CX-2009: CytomX Therapeutics
CX-2009 is a Probody drug conjugate that consists of a humanized anti-CD166 monoclonal antibody conjugated to DM4, a potent microtubule inhibitor known to be active against multiple cancer types. It is currently being tested in Phase II trial in Advanced HR-Positive/HER2-Negative Breast Cancer and of Praluzatamab Ravtansine as Monotherapy and in Combination with Pacmilimab (CX-072) in Advanced Triple-Negative Breast Cancer.
- RGT-419B: Regor Therapeutics
RGT-419B is a new generation of CDK inhibitor with an optimized kinase activity spectrum. The clinical development program of RGT-419B is designed to address the unmet medical needs of patients who are refractory or have relapsed after previous treatment, providing new opportunities to improve survival and quality of life for patients with advanced/metastatic breast cancer. It is currently being tested in Phase I trial in in subjects with Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative Advanced/Metastatic Breast Cancer.
Learn more about HR+ HER2-ve Breast Cancer Drugs opportunities in our groundbreaking HR+ HER2-ve Breast Cancer Research and development projects @ HR+ HER2-ve Breast Cancer Unmet Needs
HR+ HER2-ve Breast Cancer Companies
Regor Therapeutics, Seagen Inc., CytomX Therapeutics, Taizhou EOC Pharma, Chia Tai Tianqing Pharmaceutical Group, AstraZeneca, Daiichi Sankyo, Inc., Tyme, Inc., Context Therapeutics, Eisai Inc., Shanghai Hengrui Pharmaceutical Co., Ltd., Jiangsu Simcere Pharmaceutical Co., Kind Pharmaceuticals, Merus N.V., Atossa Therapeutics, Roche and others
HR Positive/ HER2 Negative Breast Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Intra-articular
- Intraocular
- Intrathecal
- Intravenous
- Ophthalmic
- Oral
- Parenteral
- Subcutaneous
- Topical
- Transdermal
Products have been categorized under various Molecule types such as
- Oligonucleotide
- Peptide
- Small molecule
Discover the latest advancements in HR+ HER2-ve Breast Cancer treatment by visiting our website. Stay informed about how we’re transforming the future of disease @ HR+ HER2-ve Breast Cancer Market Drivers and Barriers, and Future Perspectives
Scope of the HR+ HER2-ve Breast Cancer Pipeline Report
- Coverage- Global
- HR+ HER2-ve Breast Cancer Companies- Regor Therapeutics, Seagen Inc., CytomX Therapeutics, Taizhou EOC Pharma, Chia Tai Tianqing Pharmaceutical Group, AstraZeneca, Daiichi Sankyo, Inc., Tyme, Inc., Context Therapeutics, Eisai Inc., Shanghai Hengrui Pharmaceutical Co., Ltd., Jiangsu Simcere Pharmaceutical Co., Kind Pharmaceuticals, Merus N.V., Atossa Therapeutics, Roche and others.
- HR+ HER2-ve Breast Cancer Therapies- TQB3616 capsule, NTQ1062 with Fulvestrant, Pembrolizumab, Sacituzumab Govitecan, Dapagliflozin 10Mg Tab, SM-88, VS-6766, Abemaciclib, and others.
- HR+ HER2-ve Breast Cancer Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
- HR+ HER2-ve Breast Cancer Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
For a detailed overview of our latest research findings and future plans, read the full details of HR+ HER2-ve Breast Cancer Pipeline on our website @ HR+ HER2-ve Breast Cancer Emerging Drugs and Companies
Table of Content
- Introduction
- Executive Summary
- HR Positive/ HER2 Negative Breast Cancer: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- HR Positive/ HER2 Negative Breast Cancer– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Dato-DXd: Daiichi Sankyo, Inc.
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- CX-2009: CytomX Therapeutics
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I)
- RGT-419B: Regor Therapeutics
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Drug Name: Company Name
- Drug profiles in the detailed report…..
- Inactive Products
- HR Positive/ HER2 Negative Breast Cancer- Unmet Needs
- HR Positive/ HER2 Negative Breast Cancer- Market Drivers and Barriers
- Appendix
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