The Biliary Tract Cancer Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
“Biliary Tract Cancer Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Biliary Tract Cancer Market.
Some of the key takeaways from the Biliary Tract Cancer Pipeline Report:
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Companies across the globe are diligently working toward developing novel Biliary Tract Cancer treatment therapies with a considerable amount of success over the years.
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Biliary Tract Cancer companies working in the treatment market are Merck Sharp & Dohme, AstraZeneca, Taiho Oncology, Delcath Systems, TransThera Sciences (Nanjing), Basilea Pharmaceutica, Eisai, Zymeworks, BeiGene, Xencor, Inc., Bristol-Myers Squibb, Leap Therapeutics, Inc., Compass Therapeutics, Boehringer Ingelheim, ZielBio, Inc., GeneQuantum Healthcare (Suzhou) Co., Ltd., BioNTech SE, SOTIO Biotech, Carisma Therapeutics Inc, Rain Oncology Inc, Avacta Life Sciences Ltd, DualityBio Inc., and others, are developing therapies for the Biliary Tract Cancer treatment
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Emerging Biliary Tract Cancer therapies in the different phases of clinical trials are- Keytruda (pembrolizumab), Imfinzi (durvalumab), Futibatinib (TAS-120), Melphalan, E7090 (tasurgratinib), TT-00420, ARQ 087 (Derazantinib), Lenvima (lenvatinib), Zanidatamab, XmAb20717, Nivolumab + DKN-01, CTX-009, MEDI5752, Brigimadlin, ZB131, GQ1001, BNT141, SO-C101, CT-0508, RAIN-32, AVA6000, DB-1303, and others are expected to have a significant impact on the Biliary Tract Cancer market in the coming years.
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In April 2024, AstraZeneca has released updated exploratory findings from the TOPAZ-1 Phase III clinical trial, showing that Imfinzi (durvalumab), combined with standard-of-care chemotherapy, provided a long-term overall survival (OS) benefit in patients with advanced biliary tract cancer (BTC) at the three-year mark.
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In December 2023, RenovoRx, a clinical-stage biopharmaceutical company, has chosen Oklahoma University (OU) Health as the initial study center for its Phase III CouGar Trial of RenovoGem for treating bile duct cancer. The trial will evaluate RenovoGem specifically for unresectable locally advanced extrahepatic cholangiocarcinoma (eCCA). This pivotal, randomized trial aims to assess the efficacy and safety of trans-arterial micro-perfusion (TAMP) using the RenovoGem delivery system in combination with gemcitabine and intravenous durvalumab for treating unresectable, locally advanced eCCA.
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In December 2023, The Scottish Medicines Consortium and the UK’s National Institute of Health and Care Excellence (NICE) have endorsed AstraZeneca’s durvalumab (Imfinzi) as a first-line treatment for adults with advanced biliary tract cancers in England and Scotland. This immunotherapy should be administered alongside the chemotherapy drugs gemcitabine and cisplatin.
Biliary Tract Cancer Overview
Biliary tract cancer, also known as cholangiocarcinoma, is a type of cancer that arises in the bile ducts, which are the tubes that carry bile (a digestive fluid) from the liver to the gallbladder and small intestine.
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Emerging Biliary Tract Cancer Drugs Under Different Phases of Clinical Development Include:
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Keytruda (pembrolizumab): Merck Sharp & Dohme
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Imfinzi (durvalumab): AstraZeneca
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Futibatinib (TAS-120): Taiho Oncology
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Melphalan: Delcath Systems
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E7090 (tasurgratinib): Eisai
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TT-00420: TransThera Sciences (Nanjing)
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ARQ 087 (Derazantinib): Basilea Pharmaceutica
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Lenvima (lenvatinib): Eisai and Merck & Co
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Zanidatamab: Zymeworks and BeiGene
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XmAb20717: Xencor, Inc.
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Nivolumab + DKN-01: Bristol-Myers Squibb/Leap Therapeutics, Inc.
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CTX-009: Compass Therapeutics
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MEDI5752: AstraZeneca
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Brigimadlin: Boehringer Ingelheim
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ZB131: ZielBio, Inc.
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GQ1001: GeneQuantum Healthcare (Suzhou) Co., Ltd.
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BNT141: BioNTech SE
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SO-C101: SOTIO Biotech
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CT-0508: Carisma Therapeutics Inc
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RAIN-32: Rain Oncology Inc
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AVA6000: Avacta Life Sciences Ltd
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DB-1303: DualityBio Inc.
Biliary Tract Cancer Route of Administration
Biliary Tract Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
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Oral
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Parenteral
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Intravenous
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Subcutaneous
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Topical
Biliary Tract Cancer Molecule Type
Biliary Tract Cancer Products have been categorized under various Molecule types, such as
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Monoclonal Antibody
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Peptides
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Polymer
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Small molecule
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Gene therapy
Biliary Tract Cancer Pipeline Therapeutics Assessment
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Biliary Tract Cancer Assessment by Product Type
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Biliary Tract Cancer By Stage and Product Type
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Biliary Tract Cancer Assessment by Route of Administration
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Biliary Tract Cancer By Stage and Route of Administration
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Biliary Tract Cancer Assessment by Molecule Type
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Biliary Tract Cancer by Stage and Molecule Type
DelveInsight’s Biliary Tract Cancer Report covers around 80+ products under different phases of clinical development like
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Late-stage products (Phase III)
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Mid-stage products (Phase II)
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Early-stage product (Phase I)
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Pre-clinical and Discovery stage candidates
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Discontinued & Inactive candidates
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Route of Administration
Further Biliary Tract Cancer product details are provided in the report. Download the Biliary Tract Cancer pipeline report to learn more about the emerging Biliary Tract Cancer therapies
Some of the key companies in the Biliary Tract Cancer Therapeutics Market include:
Key companies developing therapies for Biliary Tract Cancer are – Agios Pharmaceuticals, Servier Pharmaceuticals, Merck Sharp & Dohme, AstraZeneca, Taiho Oncology, Incyte Corporation, Loxo Oncology, Bayer, Roche, Genentech, Delcath Systems, Eisai, TransThera Sciences (Nanjing), Basilea Pharmaceutica, Zymeworks, BeiGene, and others.
Biliary Tract Cancer Pipeline Analysis:
The Biliary Tract Cancer pipeline report provides insights into
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The report provides detailed insights about companies that are developing therapies for the treatment of Biliary Tract Cancer with aggregate therapies developed by each company for the same.
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It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Biliary Tract Cancer Treatment.
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Biliary Tract Cancer key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
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Biliary Tract Cancer Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
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Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Biliary Tract Cancer market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
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Biliary Tract Cancer Pipeline Market Strengths
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The therapeutic landscape in BTCs has expanded considerably in recent years. Combined therapy with chemotherapy, immunotherapy, and modulation of immune checkpoints-mediated signaling pathways are promising strategies.
Biliary Tract Cancer Pipeline Market Opportunities
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Increasing cognizance about different mutations, pathways, and other regimens has changed the focus on curable treatment options with emerging candidates that will lead the growth of the global market.
Scope of Biliary Tract Cancer Pipeline Drug Insight
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Coverage: Global
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Key Biliary Tract Cancer Companies: Merck Sharp & Dohme, AstraZeneca, Taiho Oncology, Delcath Systems, TransThera Sciences (Nanjing), Basilea Pharmaceutica, Eisai, Zymeworks, BeiGene, Xencor, Inc., Bristol-Myers Squibb, Leap Therapeutics, Inc., Compass Therapeutics, Boehringer Ingelheim, ZielBio, Inc., GeneQuantum Healthcare (Suzhou) Co., Ltd., BioNTech SE, SOTIO Biotech, Carisma Therapeutics Inc, Rain Oncology Inc, Avacta Life Sciences Ltd, DualityBio Inc., and others
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Key Biliary Tract Cancer Therapies: Keytruda (pembrolizumab), Imfinzi (durvalumab), Futibatinib (TAS-120), Melphalan, E7090 (tasurgratinib), TT-00420, ARQ 087 (Derazantinib), Lenvima (lenvatinib), Zanidatamab, XmAb20717, Nivolumab + DKN-01, CTX-009, MEDI5752, Brigimadlin, ZB131, GQ1001, BNT141, SO-C101, CT-0508, RAIN-32, AVA6000, DB-1303, and others
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Biliary Tract Cancer Therapeutic Assessment: Biliary Tract Cancer current marketed and Biliary Tract Cancer emerging therapies
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Biliary Tract Cancer Market Dynamics: Biliary Tract Cancer market drivers and Biliary Tract Cancer market barriers
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Table of Contents
1. Biliary Tract Cancer Report Introduction
2. Biliary Tract Cancer Executive Summary
3. Biliary Tract Cancer Overview
4. Biliary Tract Cancer- Analytical Perspective In-depth Commercial Assessment
5. Biliary Tract Cancer Pipeline Therapeutics
6. Biliary Tract Cancer Late Stage Products (Phase II/III)
7. Biliary Tract Cancer Mid Stage Products (Phase II)
8. Biliary Tract Cancer Early Stage Products (Phase I)
9. Biliary Tract Cancer Preclinical Stage Products
10. Biliary Tract Cancer Therapeutics Assessment
11. Biliary Tract Cancer Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Biliary Tract Cancer Key Companies
14. Biliary Tract Cancer Key Products
15. Biliary Tract Cancer Unmet Needs
16 . Biliary Tract Cancer Market Drivers and Barriers
17. Biliary Tract Cancer Future Perspectives and Conclusion
18. Biliary Tract Cancer Analyst Views
19. Appendix
20. About DelveInsight
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
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