New York, USA – August 20, 2024 – The spotlight has increasingly shone on live biotherapeutics (LBP), not just as supplements but as key players in advancing human health. Extensive research and clinical trials have highlighted their potential to serve as alternative or adjunct therapies, with applications such as probiotic capsules for treating recurrent Clostridium difficile infections, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). As this field rapidly expands, so does the need for reliable and cutting-edge production solutions tailored to these living therapeutics.
Creative Biolabs, known for driving biotechnological innovations, has the expertise and tools to tackle even the most challenging LBP research projects, whether it’s scaling up production or ensuring the quality and viability of probiotic strains.
“Probiotics are no longer just a health buzzword. They’re becoming a cornerstone in the fight against various diseases,” a scientist at Creative Biolabs said, “and probiotic research often begins at a small scale, requiring meticulous attention to detail to ensure the successful development of therapeutic candidates.”
Creative Biolabs’ probiotic lab-scale production services are designed with this in mind, offering customized solutions that cover everything from strain selection to process optimization. Tailored to support the early stages of research, these services provide researchers with the tools they need to produce probiotics in controlled, small-scale environments, to yield probiotics that are not only viable but also versatile in formulations, covering microbial freeze-dried powder, extracellular vesicles, microbiota suspension, and cell-free probiotic supernatant.
“This is crucial for proof-of-concept studies, where precision and scalability are key.” The scientist commented.
But that’s just the lay of the land. For those looking to preserve their microbial cultures, Creative Biolabs offers microbial freeze-dried powder production. The process ensures that the viability and potency of the probiotics are maintained, making it easier to store and transport them without compromising quality.
One of the most exciting developments in probiotic research is the use of extracellular vesicles (EVs). These nano-sized particles, secreted by probiotics, have shown enormous promise in modulating the immune response and delivering therapeutic molecules to specific sites within the body. Creative Biolabs can prepare commensal and probiotic-derived EVs for specific studies on their role in health and disease, such as immune regulation, as well as as a key mediator of bacteria-host interactions in the gut, including:
• Bacteroides-derived EVs
• E. coli Nissle 1917-derived EVs
• Bifidobacterium-derived EVs
• Lactobacillus-derived EVs
• Akkermansia muciniphila-derived EVs
As mentioned above, gut health is a major focus in probiotic research, and fecal microbiota transplants (FMT) have emerged as a powerful tool in restoring gut flora balance. Creative Biolabs handles the production of healthy fecal microbiota suspensions from human and animal stool samples to facilitate the research into FMT and its potential to treat various gastrointestinal disorders.
“We ensure that all instruments and solutions used in the preparation of fecal suspensions are strictly disinfected, and all fecal material preparation processes will be carried out at room temperature and preferably in an anaerobic chamber.” The scientist elaborated.
Furthermore, Creative Biolabs manages the production of cell-free probiotic supernatant, which is built for those investigating the secreted metabolites of probiotics and their effects to exert anti-inflammatory, antimicrobial, and immunomodulatory effects, offering a new avenue for probiotic-based therapies.
For more information about Creative Biolabs’ live biotherapeutic services, visit their website at https://live-biotherapeutic.creative-biolabs.com.
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Creative Biolabs delivers customized, all-in-one services for live biotherapeutics, supporting groundbreaking research in gut health and beyond.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
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Phone: 1-631-830-6441
Country: United States
Website: https://live-biotherapeutic.creative-biolabs.com