New York, USA – August 12, 2024 – The complement system has garnered attention for its critical role in immune responses and various diseases. Complement proteins are central to understanding the function of this system and its involvement in diseases. Creative Biolabs offers a variety of high-quality complement proteins, including the essential C1q protein, which is vital for research into the classical complement pathway.
Complement Proteins
“C1q is a key component of the complement cascade. Together with C1r and C1s, it forms the C1 complex, initiating the classical complement pathway. Our C1q protein products are meticulously purified and characterized to ensure high activity and reliability across various experiments,” said the Chief Scientist at Creative Biolabs.
Some other types of protein products are also recommended by Creative Biolabs, such as C1 complex, C3, C4b binding protein, C5, etc.
Below are some available protein products:
• C1 Complex: Native Human Complement C1 Complex Protein
• C3: Recombinant Human Complement C3 Protein-GST tag
• C4b Binding Protein: Recombinant Mouse C4bp Protein
• C5: Native Human Complement C5 Protein
“In addition to individual complement proteins, our platform also includes inhibitors and activators that can be used to study their effects on the complement cascade,” the Chief Scientist added.
Assay Kits
Assay kits are crucial tools for quantifying complement components and assessing their functional status. Creative Biolabs offers high-sensitivity ELISA kits to measure complement levels and activity, ensuring accuracy and reliability in research results.
“Our Mouse Complement C1q ELISA Kit is specifically designed for measuring C1q levels in mouse plasma and serum. This kit offers high sensitivity, detecting C1q as low as 0.244 ng/mL,” the scientist noted.
The complement platform also features the classical CH50 functional test kit. “This kit assesses complement activity by measuring the ability of serum to lyse antibody-coated sheep red blood cells (SRBC). It helps identify complement activity levels and detect defects or functional abnormalities in the complement pathway.”
Serum and Plasma
High-quality biological samples are often required for complement system research. Creative Biolabs provides human complement plasma and serum that are carefully processed and stored to maintain complement activity and integrity.
“For instance, our pooled complement plasma is prepared from fresh whole blood and then frozen at -80°C to preserve complement activity,” the scientist explained. This plasma is suitable for hemolytic plaque assays, complement fixation assays, and other lymphocyte toxicity and hemolysis procedures. Freezing prevents complement degradation, ensuring consistency and reliability in research.
“We also offer high-quality human serum, ideal for assays requiring a stable matrix, such as analyzing complement components and other biomarkers. Our serum products undergo rigorous processing and storage to maintain the highest quality and reliability.”
In addition to the products mentioned, Creative Biolabs’ comprehensive complement system offerings include inhibitors, peptides, and aptamer-related products.
These support a wide range of research needs:
• Basic Research: Exploring the fundamental mechanisms and regulation of the complement system.
• Disease Research: Investigating the role of the complement system in various diseases, including autoimmune diseases, infections, and cancers.
• Drug Development: Developing and testing innovative therapies to modulate complement activity.
For more information about complement products, please visit https://www.creative-biolabs.com/complement-therapeutics.
About
Creative Biolabs is dedicated to advancing complement system research through top-tier products. Its complement proteins, assay kits, and biological samples are essential tools for understanding and modulating this critical immune system component. Through these classical solutions, Creative Biolabs supports researchers in making innovative discoveries and achieving effective research outcomes.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States
Website: https://www.creative-biolabs.com/complement-therapeutics