The report “Single-Use Bioreactors Market by Product (Systems, Bags, Assemblies), Type (Stirred Tank, Bubble-Column, Wave induced), Molecule (mAbs, Vaccines), Cell Type (Mammalian, Bacterial, Yeast), Application (R&D, Bioproduction) – Global Forecast to 2029″, is projected to reach USD 9.1 billion by 2029 from USD 4.4 billion in 2024, at a CAGR of 15.4% during the forecast period of 2024 to 2029. Growing acceptance of single-use technologies among CDMOs and CMOs as SUBs offer enhanced flexibility and cost-effectiveness, lower capital investment required compared to stainless-steel systems as SUBs eliminated the need for permanent infrastructure and costly cleaning & validation procedure, lower utilization of water and energy required for cleaning & sterilization processes during use-phase of the product life cycle, and expanding biologics and biosimilar markets are some of the factors driving the expansion of the global market. Additionally, the adoption of hybrid facilities incorporating both stainless steel as well as single-use systems and untapped market potential among emerging economies presents a substantial opportunity for the SUB market.
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Global Single Uuse bioreactors Ecosystem Analysis
The SUBs market operates within a complex ecosystem that includes a wide array of stakeholders, each playing a crucial role in developing, adopting, and implementing single-use technologies. This ecosystem encompasses single-use system & consumable manufacturers, biopharmaceutical companies, CMOs, CROs, and regulatory bodies.
Sartorius AG: Leading Provider of Single-Use Bioreactor Solutions
Sartorius AG is a prominent player in the single-use bioreactors market, catering to biopharmaceutical and pharmaceutical companies, CMOs, and CROs. The company stands out for its comprehensive range of customer-centric, technology-driven solutions and significant investments in R&D. Its extensive product lineup, which includes high-quality single-use bioreactors, is a key factor in its growing market share. Sartorius AG’s robust global presence and ongoing expansion in both developed and emerging markets position it for continued growth in the single-use bioreactors sector during the forecast period.
Danaher Corporation: Key Innovator in Single-Use Bioreactors
Danaher Corporation, through its subsidiary Cytiva, offers advanced cell culture, filtration, separation, and purification technologies for the medical, biopharmaceutical, and food & beverage industries. Its strong portfolio of single-use bioreactor solutions makes it a leading player in the market. Danaher’s bioprocessing technologies facilitate the development and commercialization of drugs, plasma, and vaccines, underscoring its significant role in the single-use bioreactors market.
Thermo Fisher Scientific, Inc.: Comprehensive Single-Use Bioreactor Solutions Provider
Thermo Fisher Scientific, Inc. provides a broad range of single-use bioreactor products, effectively addressing diverse market needs. As a leading market player, Thermo Fisher leverages its extensive product offerings and strong market presence to influence trends and customer preferences. Continuous investment in R&D enables the company to stay at the cutting edge of technological advancements, addressing emerging challenges and opportunities in bioprocessing.
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Product Segmentation: Single-Use Bioreactor Systems Lead the Market
In 2023, the single-use bioreactors market is divided into several product categories: single-use bioreactor systems, single-use media bags, single-use assemblies, and other products (such as single-use vessels, sensors, tubing, connectors, software, control systems, and probes). The single-use bioreactor systems segment held the largest market share due to their lower initial investment requirements, reduced operational costs from simplified processes, and minimal environmental impact thanks to recyclable components. These advantages have significantly boosted the adoption of single-use bioreactor systems in biopharmaceutical applications.
Type Segmentation: Stirred-Tank Bioreactors Dominate
The single-use bioreactors market is segmented by type into stirred-tank, wave-induced, bubble-column, and other bioreactors (including hybrid designs and bioreactors with vertically perforated discs). In 2023, stirred-tank bioreactors represented the largest segment. Known for their versatility and scalability, stirred-tank bioreactors are extensively used in the pharmaceutical and biotechnology sectors. Their impeller-driven design ensures even distribution of gases and nutrients, making them ideal for producing recombinant proteins, vaccines, and monoclonal antibodies.
Molecule Type Segmentation: Monoclonal Antibodies Lead
The single-use bioreactors market is also segmented by molecule type into monoclonal antibodies (mAbs), vaccines, stem cells, gene-modified cells, and therapeutic proteins & peptides. In 2023, the monoclonal antibodies segment had the largest share, driven by the expanding pharmaceutical R&D pipeline, increasing cancer incidence, and rising demand for cancer therapies.
Cell Type Segmentation: Mammalian Cells Prevail
In terms of cell types, the market is divided into mammalian cells, bacterial cells, yeast cells, and other cells (such as insect and plant cells). The mammalian cells segment held the largest market share in 2023. This is due to the widespread use of mammalian cells in bioprocessing, known for their sophisticated metabolic functions, which drive the segment’s growth.
Application Segmentation: Bioproduction Leads
The market is segmented by application into bioproduction, process development, and research & development (R&D). The bioproduction segment accounted for the largest share in 2023, attributed to the growing use of single-use bioreactors in biomanufacturing, increased regulatory approvals for biopharmaceuticals, the rise of biosimilars, and patent expirations of blockbuster drugs.
End-User Segmentation: Pharmaceutical & Biotechnology Companies Dominate
Based on end users, the market is segmented into pharmaceutical & biotechnology companies, contract research organizations (CROs) & contract manufacturing organizations (CMOs), and academic & research institutes. The pharmaceutical & biotechnology companies segment was the largest in 2023 due to heightened R&D activities and increased production of biologics and biosimilars.
Regional Insights: North America and Asia Pacific Lead
The market is divided by region into North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. In 2023, North America held the largest market share, followed by Europe. North America’s substantial market share is driven by the presence of major players and growing demand for personalized medicine and biologics. Meanwhile, the Asia Pacific region is anticipated to experience the highest compound annual growth rate (CAGR), fueled by the rising demand for biosimilars, expanding biopharmaceutical manufacturing capacities, and a growing contract manufacturing sector.
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