Several major pharma and biotech giants, such as Loxo Oncology, TG Therapeutics, BeiGene, Gilead Sciences, and various others, are actively involved in developing therapies for Chronic Lymphocytic Leukemia.
DelveInsight’s “Chronic Lymphocytic Leukemia Market Insights, Epidemiology, and Market Forecast 2032” report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Chronic Lymphocytic Leukemia market size, share, trends, and growth opportunities in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).
The Chronic Lymphocytic Leukemia market report covers emerging drugs, current treatment practices, market share of individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, key drivers & barriers impacting the market growth, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Chronic Lymphocytic Leukemia Overview
Chronic Lymphocytic Leukemia (CLL) or small lymphocytic lymphoma (SLL) represents a slow-growing cancer marked by an excessive production of mature yet dysfunctional B lymphocytes. Pathologically and immunophenotypically, CLL and SLL are identical. Both stem from B-cell lymphocytes but manifest differently depending on the location of abnormal cell accumulation. Initially, the leukemic phase, known as CLL, involves the presence of these cells in the bloodstream. Subsequently, this progresses to the lymphoma phase, termed SLL, where the cells are predominantly found in the lymph nodes.
CLL/SLL constitutes a monoclonal lymphoproliferative disorder characterized by the abnormal proliferation and buildup of morphologically mature yet functionally impaired B-cell lymphocytes. Predominant sites of the disease include peripheral blood, spleen, lymph nodes, and bone marrow.
The precise cause of Chronic Lymphocytic Leukemia remains elusive. Genetic factors are believed to play a significant role, with environmental influences having a lesser impact. However, certain known risk factors include occupational exposure to specific chemicals, radiation, and tobacco use.
Chronic Lymphocytic Leukemia Market Key Facts
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According to Surveillance, Epidemiology, and End Results (SEER), the rate of new cases of chronic lymphocytic leukemia was 4.7 per 100,000 men and women per year. These rates are age-adjusted and based on 2015–2019 cases and 2016–2020 deaths.
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According to Kajuter et al. 2021, The age-standardized incidence rate is four to five cases per 100,000 person-years, and about 5500 patients in Germany are newly diagnosed with Chronic Lymphocytic Leukemia annually. Men are more often affected than women.
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According to Cancer Research UK, Over the last decade, chronic lymphocytic leukemia incidence rates have increased by around a tenth (9%) in the UK. Rates in females have remained stable, and rates in males have increased by more than a twentieth (7%) (2015-2017).
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According to Quinquenel et al. 2020, in 2018, the estimated number of new incident cases of Chronic Lymphocytic Leukemia in France was 4674. The male predominance is marked, with 59.3% of Chronic Lymphocytic Leukemia cases identified in men (2770 patients) and 40.7% of cases identified in women (1904 patients).4 The median age at diagnosis is 71 years in men and 73 years in women.
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On January 19, 2023, the U.S. Food and Drug Administration (FDA) granted approval to BeiGene’s Brukinsa (Zanubrutinib), a Bruton’s tyrosine kinase inhibitor, for the treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Chronic Lymphocytic Leukemia Market
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted Chronic Lymphocytic Leukemia market size by analyzing the impact of current and emerging pipeline therapies. It also provides a thorough assessment of the market drivers & barriers, unmet needs, and emerging technologies set to impact the market dynamics.
The report gives complete detail of the Chronic Lymphocytic Leukemia market trend for each marketed drug and mid & late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, their Mechanism of Action (MOA), Route of Administration (ROA), molecule types, competition with other therapies, brand value, and their impact on the market.
Chronic Lymphocytic Leukemia Epidemiology Assessment
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted epidemiology trends by exploring numerous studies and research. The epidemiology section also provides a detailed analysis of diagnosed and prevalent patient pool, future trends, and views of key opinion leaders.
The Report Covers the Chronic Lymphocytic Leukemia (CLL) Epidemiology Segmented by –
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Total Incidence of Chronic Lymphocytic Leukemia in the 7MM (2019–2032)
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Age-specific Incidence of Chronic Lymphocytic Leukemia in the 7MM (2019–2032)
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Treatable Cases of Chronic Lymphocytic Leukemia in the 7MM (2019–2032)
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Gender-specific Incidence of Chronic Lymphocytic Leukemia in the 7MM (2019–2032)
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Relapsed and Refractory Cases of Chronic Lymphocytic Leukemia in the 7MM (2019–2032)
Chronic Lymphocytic Leukemia Drugs Uptake and Pipeline Development Activities
The drug uptake section focuses on the rate of uptake of the potential drugs recently launched in the Chronic Lymphocytic Leukemia market or expected to be launched during the study period. The analysis covers the Chronic Lymphocytic Leukemia market uptake by drugs, patient uptake by therapies, and sales of each drug. Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Chronic Lymphocytic Leukemia pipeline development activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyses recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
Learn How the Chronic Lymphocytic Leukemia Market Will Evolve and Grow by 2032 @ https://www.delveinsight.com/sample-request/chronic-lymphocytic-leukemia-cll-market
Chronic Lymphocytic Leukemia Therapeutics Analysis
Several major pharma and biotech giants are actively developing therapies for Chronic Lymphocytic Leukemia (CLL). Currently, TG Therapeutics is leading the therapeutics market with its Chronic Lymphocytic Leukemia (CLL) drug candidates in the most advanced stage of clinical development.
The Leading Companies in the Chronic Lymphocytic Leukemia (CLL) Therapeutics Market Include:
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AFA Insurance
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Astex Pharmaceuticals
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BeiGene
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Bristol Myers Squibb
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Celgene
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Cellectar Biosciences, Inc.
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Gilead Sciences
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Incyte Corporation
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IO Biotech
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Janssen Research & Development, LLC
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Loxo Oncology
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MorphoSys AG
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Novartis
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Octapharma
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Oncternal Therapeutics
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TG Therapeutics
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TG therapeutics
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Zhejiang DTRM Biopharma
And Many More
Chronic Lymphocytic Leukemia (CLL) Drugs Covered in the Report Include:
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Ublituximab: TG Therapeutics
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LOXO305: Loxo Oncology
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Cirmtuzumab: Oncternal Therapeutics
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Olaptesed pegol: NOXXON Pharma
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Zanubrutinib: BeiGene
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KTE-X19: Kite, a Gilead Company
And Many More
The Report Covers the In-depth Assessment of the Emerging Drugs & Key Companies. Download the Sample Report to Learn More @ https://www.delveinsight.com/sample-request/chronic-lymphocytic-leukemia-cll-market
Table of Contents
1. Key Insights
2. Executive Summary
3. Chronic Lymphocytic Leukemia Competitive Intelligence Analysis
4. Chronic Lymphocytic Leukemia Market Overview at a Glance
5. Chronic Lymphocytic Leukemia Disease Background and Overview
6. Chronic Lymphocytic Leukemia Patient Journey
7. Chronic Lymphocytic Leukemia Epidemiology and Patient Population (In the US, EU5, and Japan)
8. Chronic Lymphocytic Leukemia Treatment Algorithm, Current Treatment, and Medical Practices
9. Chronic Lymphocytic Leukemia Unmet Needs
10. Key Endpoints of Chronic Lymphocytic Leukemia Treatment
11. Chronic Lymphocytic Leukemia Marketed Products
12. Chronic Lymphocytic Leukemia Emerging Drugs and Latest Therapeutic Advances
13. Chronic Lymphocytic Leukemia Seven Major Market Analysis
14. Attribute Analysis
15. Chronic Lymphocytic Leukemia Market Outlook (In US, EU5, and Japan)
16. Chronic Lymphocytic Leukemia Access and Reimbursement Overview
17. KOL Views on the Chronic Lymphocytic Leukemia Market
18. Chronic Lymphocytic Leukemia Market Drivers
19. Chronic Lymphocytic Leukemia Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
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