New York, USA – February 22, 2024 – “Bispecific antibodies (bsAb) represent a biomedical breakthrough, with the ability to simultaneously target two distinct antigens. This unique capability positions bispecific antibodies as promising tools in cancer therapy, immunotherapy, and various other fields. However, the development of efficient bsAbs is a complex endeavor, demanding advanced techniques and specialized expertise,” remarked a scientist at Creative Biolabs.
Creative Biolabs’ bsAb engineering services encompass the development of bsAb fragments alongside custom construction and production of bsAb conjugates. Through these services, researchers can tailor-design bsAbs with specific structures and functions to meet their individual needs and research objectives, enabling dual binding to diverse antigens.
In the domain of bispecific antibody fragment development, Creative Biolabs employs advanced genetic engineering techniques to design and fabricate various bsAb fragments, catering to clients’ specific requirements. “Bispecific antibody fragments exhibit diverse characteristics, such as lacking partial or complete antibody constant domains. These fragments not only demonstrate high affinity and multivalency but also showcase enhanced tissue penetration in immunotherapy.”
Creative Biolabs emphasizes its recombinant antibody synthesis platform, seamlessly integrating multiple biotechnology platforms into a streamlined workflow that saves both budget and time. “This facilitates the provision of bsAb fragment products targeting any desired antigen pairs, including scFv-Fab fragments, scFv fragments, Tandem scFv, among others.”
Moreover, Creative Biolabs’ services extend beyond bsAb design and construction to encompass expression, production, and functional assessment of bsAbs. Through a series of rigorous experiments and tests, the bsAb products provided ensure superior quality and reliability.
“While the conventional method for bispecific antibody generation involves DNA engineering fusion, a considerable number of bsAbs can also be obtained through chemical cross-linking. We leverage various starting materials or fusion parts to generate bispecific antibody conjugates,” explained the scientist.
Creative Biolabs can assist in generating bsAb conjugates, including but not limited to:
* Antibody-antibody conjugates: Generated through the use of different starting antibodies, cross-linking reagents, and conjugation strategies.
* Antibody-peptide conjugates: A novel drug utilizing small molecules as guides instead of monoclonal antibodies.
* BsAb functional conjugates: Integrating multiple functionalities through cross-linking agents.
For more information about bispecific antibody engineering services, please visit https://www.creative-biolabs.com/bsab.
About Creative Biolabs
Creative Biolabs supports researchers in developing customized bispecific antibodies tailored to their specific requirements through bespoke bsAb engineering services, thereby introducing new hope and opportunities to scientific research. As the demand for bispecific antibodies continues to rise, Creative Biolabs remains committed to maintaining its leading position, delivering even more innovative solutions to its customers.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States
Website: https://www.creative-biolabs.com/bsab