DelveInsight’s, “Alzheimer’s Disease Pipeline Insights 2023” report provides comprehensive insights about 150+ companies and 160+ pipeline drugs in Alzheimer’s Disease pipeline landscape. It covers the Alzheimer’s Disease pipeline drug profiles, including Alzheimer’s Disease clinical trials and nonclinical stage products. It also covers the Alzheimer’s Disease therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To explore more information on the latest breakthroughs in the Alzheimer’s Disease Pipeline treatment landscape of the report, click here @ Alzheimer’s Disease Pipeline Outlook
Key Takeaways from the Alzheimer’s Disease Pipeline Report
- DelveInsight’s Alzheimer’s Disease Pipeline report depicts a robust space with 150+ active players working to develop 160+ pipeline therapies for Alzheimer’s Disease.
- The leading Alzheimer’s Disease Companies include Biogen, AZTherapies, Cerecin, Neurotrope, Synaptogenix, INmune Bio, Cassava Sciences, EIP Pharma, Neuraly, AB Science, Cortexyme, Anavex Life Sciences, Athira Pharma, Time Therapeutics, Denali Therapeutics Inc., Alector Inc., Lexeo Therapeutics, TrueBinding, Inc., Vaccinex Inc., Annovis Bio Inc., Eisai Inc., Hoffmann-La Roche, Ionis Pharmaceuticals, Otsuka Pharmaceutical, Cognition Therapeutics, Merck Sharp & Dohme LLC, ImmunoBrain Checkpoint, AbbVie, AriBio Co., Ltd., Oryzon Genomics S.A., Eli Lilly and Company, Neurokine Therapeutics, Excelsior, Seelos Therapeutics Inc., Janssen Research & Development, Shanghai Hengrui Pharmaceutical, reMYND, Alzinova AB, VTBIO Co. LTD, BioVie Inc., Prothena Corporation, Coya Therapeutics Inc., and others
- Promising Alzheimer’s Disease Pipeline Therapies include ALZT-OP1, Tricaprilin, Bryostatin-1, INB03, Sumifilam, Neflamapimod, Pegylated exenatide, NLY-02, Masitinib, Atuzaginstat, COR588, Blarcamesine, NDX-1017, Bromocriptine, DNL788, AL002, CMS121, LX1001, TB006, Pepinemab, Posiphen, E2814, RO7126209, IONIS MAPTRx, Brexpiprazole, CT1812, MK-1942, IBC Ab002, ABBV-916, AR1001, ORY-2001, LY3372689, MW150, EX039, SLS-005, Seltorexant, Donanemab, SHR-1707, REM0046127, ALZ-101, VT301, NE3107, PRX005, MK-6240, and others.
- Alzheimer’s Disease Companies and academics are working to assess challenges and seek opportunities that could influence Pheochromocytoma R&D. The Alzheimer’s Disease pipeline therapies under development are focused on novel approaches to treat/improve Alzheimer’s Disease.
For further information, refer to the detailed Alzheimer’s Disease Unmet Needs, Alzheimer’s Disease Market Drivers, and Alzheimer’s Disease Market Barriers, click here for Alzheimer’s Disease Ongoing Clinical Trial Analysis
Alzheimer’s Disease Overview
Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. In most people with the disease — those with the late-onset type symptoms first appear in their mid-60s. Early-onset Alzheimer’s occurs between a person’s 30s and mid-60s and is very rare. Alzheimer’s disease is the most common cause of dementia among older adults.
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Alzheimer’s Disease Emerging Drugs Profile
- Donanemab: Eli Lilly and Company
Donanemab is a humanized IgG1 antibody directed at an N-terminal pyroglutamate Aβ epitope that is present only in established plaques. It is specific for this epitope and shows no off-target binding to other Aβ species, neurotransmitters, or their receptors and has no known symptomatic effect. In a phase 1a study involving patients with amyloid-positive prodromal-to-moderate Alzheimer’s disease, the safety, pharmacokinetics, and pharmacodynamics of donanemab were assessed after the administration of multiple doses.
- Masitinib: AB Science
Masitinib (AB1010) is an oral tyrosine kinase inhibitor that has demonstrated neuroprotective action in neurodegenerative diseases via inhibition of mast cell and microglia/macrophage activity, possibly by switching the neuroimmune system from a neurotoxic state towards a neuroprotective state through remodeling of the neuronal microenvironment.The rationale to use masitinib in Alzheimer’s disease patients is supported by preclinical evidence demonstrating that the pharmacological action of masitinib in mast cells can restore normal spatial learning performance in a mouse model of Alzheimer’s disease and promotes recovery of synaptic markers. Currently, the drug is in Phase III stage of Clinical trial evaluation for the treatment of Alzheimer Disease.
- XPro1595 (Pegipanermin): INmune Bio, Inc.
XPro1595 is a next-generation inhibitor of tumor necrosis factor (TNF) that uses a dominant-negativeTNF technology that is very different from approved TNF inhibitors that block the effects of both soluble and trans-membrane TNF. Pegipanermin neutralizes soluble TNF, without affecting trans-membrane TNF or TNF receptors. XPro1595 could have substantial beneficial effects in patients with Alzheimer’s and other neurodegenerative diseases by decreasing neuroinflammation. Currently the drug is in Phase II stage of Clinical trial evaluation for the treatment of Alzheimer’s disease.
Dive deep into rich insights for drugs for Alzheimer’s Disease Market Drivers and Alzheimer’s Disease Market Barriers, click here @ Alzheimer’s Disease Unmet Needs and Analyst Views
Alzheimer’s Disease Pipeline Therapeutics Assessment
There are approx. 150+ key companies which are developing the therapies for Alzheimer’s disease. The companies which have their Alzheimer’s disease drug candidates in the most advanced stage, i.e. Preregistration include, Eli Lilly and Company.
Scope of the Alzheimer’s Disease Pipeline Report
- Coverage- Global
- Alzheimer’s Disease Companies- Biogen, AZTherapies, Cerecin, Neurotrope, Synaptogenix, INmune Bio, Cassava Sciences, EIP Pharma, Neuraly, AB Science, Cortexyme, Anavex Life Sciences, Athira Pharma, Time Therapeutics, Denali Therapeutics Inc., Alector Inc., Lexeo Therapeutics, TrueBinding, Inc., Vaccinex Inc., Annovis Bio Inc., Eisai Inc., Hoffmann-La Roche, Ionis Pharmaceuticals, Otsuka Pharmaceutical, Cognition Therapeutics, Merck Sharp & Dohme LLC, ImmunoBrain Checkpoint, AbbVie, AriBio Co., Ltd., Oryzon Genomics S.A., Eli Lilly and Company, Neurokine Therapeutics, Excelsior, Seelos Therapeutics Inc., Janssen Research & Development, Shanghai Hengrui Pharmaceutical, reMYND, Alzinova AB, VTBIO Co. LTD, BioVie Inc., Prothena Corporation, Coya Therapeutics Inc., and others
- Alzheimer’s Disease Pipeline Therapies- ALZT-OP1, Tricaprilin, Bryostatin-1, INB03, Sumifilam, Neflamapimod, Pegylated exenatide, NLY-02, Masitinib, Atuzaginstat, COR588, Blarcamesine, NDX-1017, Bromocriptine, DNL788, AL002, CMS121, LX1001, TB006, Pepinemab, Posiphen, E2814, RO7126209, IONIS MAPTRx, Brexpiprazole, CT1812, MK-1942, IBC Ab002, ABBV-916, AR1001, ORY-2001, LY3372689, MW150, EX039, SLS-005, Seltorexant, Donanemab, SHR-1707, REM0046127, ALZ-101, VT301, NE3107, PRX005, MK-6240, and others.
- Alzheimer’s Disease Pipeline Segmentation: Product Type, Molecule Type, Route of Administration
Got Queries? Find out the related information on Alzheimer’s Disease Mergers and acquisitions, Alzheimer’s Disease Licensing Activities @ Alzheimer’s Disease Emerging Drugs, and Recent Trends
Table of Content
- Introduction
- Executive Summary
- Alzheimer’s Disease: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- Alzheimer’s Disease– DelveInsight’s Analytical Perspective
- Late Stage Products (Preregistration)
- Donanemab: Eli Lilly and Company
- Late Stage Products (Phase III)
- Masitinib: AB Science
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- XPro1595 (Pegipanermin): INmune Bio, Inc.
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I)
- Drug Name: Company Name
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Drug Name: Company Name
- Drug profiles in the detailed report…..
- Inactive Products
- Alzheimer’s Disease Key Companies
- Alzheimer’s Disease Key Products
- Alzheimer’s Disease- Unmet Needs
- Alzheimer’s Disease- Market Drivers and Barriers
- Alzheimer’s Disease- Future Perspectives and Conclusion
- Alzheimer’s Disease Analyst Views
- Alzheimer’s Disease Key Companies
- Appendix
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